II. Indication
- Open Angle Glaucoma second line agent (adjunctive)
III. Mechanism
- Reduces resistance to aqueous outflow
IV. Medications
-
Cholinergic Agonists
- Pilocarpine (Isoptocarpine, Pilopine gel, Ocusert, Pilocar) 1 drop four times daily
- Carbachol (Isopto Carbachol)
-
Anticholinesterases
- Echothiophate (Phospholine Iodide)
- Demacarium (Humorsol)
V. Adverse Effects
- Generally well tolerated
- Pupil Constriction (primary expected effect)
- Systemic effects (if absorbed)
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Related Studies
| pilocar (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| PILOCARPINE 1% EYE DROPS | Generic | $3.88 per ml |
| PILOCARPINE 2% EYE DROPS | Generic | $3.55 per ml |
| PILOCARPINE 4% EYE DROPS | Generic | $3.54 per ml |
| PILOCARPINE HCL 5 MG TABLET | Generic | $0.25 each |
| PILOCARPINE HCL 7.5 MG TABLET | Generic | $0.62 each |