Ophthalmic Cyclosporine

Aka: Ophthalmic Cyclosporine, Ophthalmic Calcineurin Inhibitor, Restasis, Cyclosporine Ophthalmic Emulsion, Cyclosporine Ophthalmic Suspension

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II. Indications

  1. Keratoconjunctivitis Sicca (Sjogren's Syndrome)

III. Mechanism

  1. Cyclosporine is a Calcineurin Inhibitor with Immunosuppression and antiinflammatory properties (esp. inhibits T-Helper Cells)
  2. Improves tear production in autoimmune disorders (esp. Sjogren's Syndrome)

IV. Medications

  1. Restasis 0.05% emulsion (preferred as generic option, $200/month)
  2. Other non-generic options (at $500-$800 per month)
    1. Cequa 0.09% solution
    2. Veyve 0.1% solution

V. Dosing

  1. Use 1 drop in each eye every 12 hours
  2. Remove contacts before instilling drops (and wait 15 min before reinserting)
  3. Separate from other ophthalmic topicals by at least 15 minutes

VI. References

  1. (2025) Presc Insights 32(11): 66

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Cost: Medications

restasis (on 10/19/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
RESTASIS 0.05% EYE EMULSION Generic $3.93 each
RESTASIS MULTIDOSE 0.05% EYE $112.47 per ml
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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