II. Indications
III. Mechanism
- Decrease Aqueous Humor production and increases outflow (lowers IOP 20 to 25%)
IV. Medications (purple cap)
- Apraclonidine (Lopidine)
- Brimonidine (Alphagan)
- Available as combination with Brinzolamide (Simbrinza)
- Mirvaso (Brimonidine gel)
- Indicated for Eye Redness due to Rosacea
- Lumify (OTC Brimonidine 0.025%) released in 2018
- Marketed as OTC to reduce Eye Redness
- No proof that it is more effective than OTC ocular Decongestants (e.g. visine) and more expensive
- Evaluate Eye Redness for underlying cause instead
- (2018) presc lett 25(6): 35 [PubMed]
V. Drug Interactions
VI. Adverse Effects
- Eye itching, burning or stinging
- Dry Mouth
VII. Efficacy
- Less effective than Intraocular Beta Blocker and Intraocular Prostaglandin
VIII. References
Images: Related links to external sites (from Bing)
Related Studies
| apraclonidine (on 9/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| APRACLONIDINE HCL 0.5% DROPS | Generic | $11.32 per ml |
| brimonidine (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BRIMONIDINE 0.2% EYE DROP | Generic | $0.74 per ml |
| BRIMONIDINE 0.33% GEL PUMP | Generic | $14.63 per gram |
| BRIMONIDINE TARTRATE 0.1% DROP | Generic | $30.21 per ml |
| BRIMONIDINE TARTRATE 0.15% DRP | Generic | $23.45 per ml |
| BRIMONIDINE-TIMOLOL 0.2%-0.5% | Generic | $27.65 per ml |
| alphagan (on 1/14/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| ALPHAGAN P 0.1% DROPS | $35.54 per ml | |
| ALPHAGAN P 0.15% EYE DROPS | Generic | $23.45 per ml |
| lumify (on 3/23/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| LUMIFY 0.025% EYE DROP | OTC | $2.99 per ml |