II. Precautions

  1. Consult ophthalmology regarding the use of ocular Corticosteroids
  2. Ocular Corticosteroid use is high risk, esp. if signs of infection, or other risks
    1. Immunocompromised
    2. Globe Rupture
    3. Contaminated Eye Trauma (e.g. organic material)

III. Preparations: Corticosteroids Alone

  1. Higher Potency
    1. Dexamethasone (0.1% solution)
    2. Prednisolone acetate suspension or PrednisoloneSodium Phosphate Solution (1%)
  2. Lower Potency (less effect on Intraocular Pressure)
    1. Dexamethasone (0.05% ointment)
    2. Prednisolone acetate suspension or PrednisoloneSodium Phosphate Solution (0.125%)
    3. Lotreprednol etabonate suspension (0.2%, 0.5%)
    4. Fluoromethalone (0.1% ointment or suspenstion)
    5. Medrysone suspension (1%)
    6. Rimexolone suspension (1%)

IV. Preparations: Antibiotic AND Corticosteroid Combinations (not recommended)

  1. Precaution
    1. Trobe (see reference below) cautions against use
    2. Reduced inflammation and pain, despite ongoing serious infection
  2. Gentamicin
    1. With Prednisolone (Pred G)
  3. Neomycin-Polymyxin
    1. With Dexamethasone (Maxitrol)
  4. Tobramycin
    1. With Dexamethasone (Tobradex)
    2. With Loteprednol (Zylet)
  5. Sulfacetamide
    1. With Prednisolone (Vasocidin, Blephamide, FML-S Liquifilm)

V. Adverse Effects

  1. Ocular perforation
  2. Ocular Sepsis
  3. Increased Intraocular Pressure (Glaucoma)

VI. References

  1. Trobe (2012) Physicians Guide to the Eye, 4th ed, AAO, San Francisco, p. 180-81

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