II. Precautions
- Consult ophthalmology regarding the use of ocular Corticosteroids
- Ocular Corticosteroid use is high risk, esp. if signs of infection, or other risks
- Immunocompromised
- Globe Rupture
- Contaminated Eye Trauma (e.g. organic material)
III. Preparations: Corticosteroids Alone
- Higher Potency
- Dexamethasone (0.1% solution)
- Prednisolone acetate suspension or Prednisolone Sodium phosphate Solution (1%)
- Lower Potency (less effect on Intraocular Pressure)
- Dexamethasone (0.05% ointment)
- Prednisolone acetate suspension or Prednisolone Sodium phosphate Solution (0.125%)
- Lotreprednol etabonate suspension (0.2%, 0.5%)
- Fluoromethalone (0.1% ointment or suspenstion)
- Medrysone suspension (1%)
- Rimexolone suspension (1%)
IV. Preparations: Antibiotic AND Corticosteroid Combinations (not recommended)
- Precaution
- Trobe (see reference below) cautions against use
- Reduced inflammation and pain, despite ongoing serious infection
-
Gentamicin
- With Prednisolone (Pred G)
- Neomycin-Polymyxin
- With Dexamethasone (Maxitrol)
-
Tobramycin
- With Dexamethasone (Tobradex)
- With Loteprednol (Zylet)
- Sulfacetamide
- With Prednisolone (Vasocidin, Blephamide, FML-S Liquifilm)
V. Adverse Effects
- Ocular perforation
- Ocular Sepsis
- Increased Intraocular Pressure (Glaucoma)
VI. References
- Trobe (2012) Physicians Guide to the Eye, 4th ed, AAO, San Francisco, p. 180-81