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Definition (MSH)
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A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
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| Concepts |
Disease or Syndrome
(T047)
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| MSH |
D017241
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| ICD10 |
E88.41
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| SnomedCT |
39925003, 240097009 |
| English |
Syndrome, MELAS, MELAS-Mito enc lact ac & strok, MELAS-Mitochond encephal, lactic acidos & strokelike episode, Mitoch enc lact ac & strlik ep, Mitochond encephalopathy, lact acidosis & strokelike episode, MELAS - Mitochond myop/encephal/lact acidos/strke-like episo, MELAS Mito myo/enceph/lac/strk, Mitoch myop/enceph/lact/strke, Mitoch myopath/encephalopath/lactic acidos/strke-like episod, MITOCHONDRIAL MYOPATHY, ENCEPHALOPATHY, LACTIC ACIDOSIS, AND STROKE-LIKE EPISODES, MELAS SYNDROME, MELAS Syndrome, Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes, Juvenile myopathy, encephalopathy, lactic acidosis and stroke, mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS), mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS) (diagnosis), Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes, Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode, MELAS Syndrome [Disease/Finding], syndrome melas, melas syndrome, mela, melas, mela syndrome, Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes, Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes, MELAS, Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke, MELAS syndrome, Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (disorder), MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, MELAS - Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes, Juvenile myopathy, encephalopathy, lactic acidosis AND stroke (disorder), Juvenile myopathy, encephalopathy, lactic acidosis AND stroke, Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (disorder) |
| Japanese |
ＭＥＬＡＳ症候群, MELASｼｮｳｺｳｸﾞﾝ, ミトコンドリア脳筋症・乳酸アシドーシス・脳卒中様発作症候群, ﾐﾄｺﾝﾄﾞﾘｱﾉｳｷﾝｼｮｳﾆｭｳｻﾝｱｼﾄﾞｰｼｽﾉｳｿｯﾁｭｳﾖｳﾎｯｻｼｮｳｺｳｸﾞﾝ, MELAS症候群 |
| Swedish |
MELAS-syndrom
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| Czech |
syndrom MELAS, Mitochondrickál encefalomyopatie s mléčnou acidózou a epizodami podobnými mrtvici, MELAS syndrom |
| Spanish |
Encefalopatía mitocondrial con acidosis láctica y episodios tipo ictus, Miopatía, Encefalopatía Mitocondrial, Acidosis Láctica y Episodio Similar a ACV, Miopatía, Encefalopatía Mitocondrial, Acidosis Láctica y Episodio Stroke-Like, Miopatía Mitocondrial, Acidosis Láctica y Episodio Tipo Ictus, miopatía juvenil, encefalopatía, acidosis láctica Y ACV, miopatía juvenil, encefalopatía, acidosis láctica Y accidente cerebrovascular (trastorno), miopatía juvenil, encefalopatía, acidosis láctica Y accidente cerebrovascular, Síndrome de MELAS, Miopatía Mitocondrial con Acidosis Láctica y Episodio Similar a Ataque, Síndrome MELAS |
| French |
Encéphalomyopathie mitochondriale avec acidose lactique et pseudo accidents vasculaires, Syndrome MELAS, Myopathie mitochondriale-encéphalopathie-acidose lactique |
| Dutch |
mitochondriale encefalopathie met melkzuuracidose en stroke-like aanvallen, MELAS syndroom, MELAS-syndroom, Mitochondriale myopathie, melkzuuracidose, 'stroke-like' episoden, Syndroom, MELAS- |
| Portuguese |
Encefalopatía mitocondrial con acidosis láctica e episódios tipo ictus, Episódio de Miopatia Mitocondrial, Acidose Láctica, Semelhante a Acidente Vascular Cerebral, Episódio de Miopatia Mitocondrial, Acidose Láctica, Semelhante a Icto Cerebral, Miopatia Mitocondrial, Encefalopatia, Acidose Láctica e Episódios tipo AVC, Síndrome de MELAS, Síndrome MELAS |
| German |
mitochondriale Enzephalomyopathie mit Laktatazidose und schlaganfallaehnlichen Episoden, Melas Syndrom, MELAS-Syndrom, Mitochondriale Myopathie, Laktatazidose, schlaganfallähnliche Episode |
| Italian |
Encefalomiopatia mitocondriale con acidosi lattica ed episodi simili ad ictus, Miopatia mitocondriale, acidosi lattica ed episodi ictus-simili, Sindrome MELAS |
| Finnish |
MELAS-oireyhtymä
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| Russian |
MELAS SINDROM, MELAS СИНДРОМ |
| Polish |
Zespół MELAS
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| Hungarian |
MELAS syndroma, Mitochondrialis encephalomyopathia laktát acidosissal és sztrók-szerű episodokkal |
| Norwegian |
Mitokondrial myopati, laktacidose og slagliknede episoder, MELAS-syndrom, MELAS |
