Anticyclic Citrullinated Peptide Antibody

Aka: Anticyclic Citrullinated Peptide Antibody, Anti-cyclic Citrullinated Peptide Antibody, Anti-Citrullinated Protein Antibody

advertisement

II. Indications

  1. Rheumatoid Arthritis Diagnosis confirmation
    1. Rheumatoid Factor or Antinuclear Antibody positive
    2. May also predict prognosis and erosive disease likelihood
    3. Does not correlate to therapy response (not used for monitoring)

III. Mechanism

  1. Enzyme-linked Immunosorbent Assay (ELISA)

IV. Efficacy: Rheumatoid Arthritis Diagnosis

  1. Test Sensitivity: 67%
  2. Test Specificity: 95%
  3. Positive Likelihood Ratio (LR+): 12.46
  4. Negative Likelihood Ratio (LR-): 0.36

V. References

  1. Ali (2018) Am Fam Physician 98(3): 164-70 [PubMed]
  2. Barra (2011) Rheumatology 50(2): 311-6 [PubMed]
  3. Nishimura (2007) Ann Intern Med 146(11): &97-808 [PubMed]

Images: Related links to external sites (from Bing)

These images are a random sampling from a Bing search on the term "Anticyclic Citrullinated Peptide Antibody." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images

Related Studies

Related Topics in Pathology and Laboratory Medicine

advertisement