Anti-ribonucleoprotein Antibody

Aka: Anti-ribonucleoprotein Antibody, Anti-RNP Antibody, Anti-U1 snRNP Antibody, Ribonucleoprotein Antibody, Anti-RNP, Anti-U1 snRNP

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II. Causes: Negative

  1. Normal

III. Causes: Positive (percentage refers to sensitivity)

  1. Systemic Lupus Erythematosus (30-40%)
    1. Correlates with disease activity
  2. Rheumatoid Arthritis (10%)
  3. Sjogren's Syndrome (15%)
  4. Mixed Connective Tissue Disease (95%)
  5. Systemic Sclerosis (30%)
  6. Drug Induced Lupus (<5%)

IV. References

  1. Gladman in Klippel (1997) Rheumatic Diseases p. 255-6
  2. Peng in Ruddy (2001) Kelley's Rheumatology, p. 161-72
  3. Callegari (1995) Postgrad Med, 97(4):65-74 [PubMed]
  4. Lane (2002) Am Fam Physician 65(6):1073-80 [PubMed]

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Related Studies

Ontology: Ribosomal ribonucleoprotein antibody (C0443935)

Concepts Amino Acid, Peptide, or Protein (T116) , Immunologic Factor (T129)
SnomedCT 26812001, 103175005, 259927002
LNC LP39569-6, MTHU007629
English RNP - Ribonucleoprotein ab, Ribosomal ribonucleoprotein ab, anti rnp antibody, antibodies rnp, anti rnp, rnp antibody, anti-rnp, Anti RNP antibody (substance), Anti-nRNP antibody (substance), Antinuclear ribonucleoprotein antibody, Anti RNP antibody, Anti ribonucleoprotein antibody, Anti-nRNP antibody, Ribonucleoprotein extractable nuclear Ab, Ribonucleoprotein extractable nuclear Antibody, Anti Rnp Antibody, Ribosomal ribonucleoprotein antibody, RNP - Ribonucleoprotein antibody, Ribonucleoprotein antibody, Ribosomal ribonucleoprotein antibody (substance), RNP antibody, Anti-RNP, Anti-nRNP
Spanish anticuerpo antinuclear ribonucleoproteína, anticuerpo anti - nRNP, anticuerpo anti - nRNP (sustancia), anticuerpo antirribonucleoproteína, anticuerpo anti RNP, anticuerpo anti RNP (sustancia), anticuerpo antirribonucleoproteína ribosómica (sustancia), anticuerpo antirribonucleoproteína ribosómica
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Anti-U1 RNP antibody (C0522299)

Concepts Amino Acid, Peptide, or Protein (T116) , Immunologic Factor (T129)
SnomedCT 103175005
English Anti-U1 RNP antibody
Spanish anticuerpo anti - U1 RNP
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pathology and Laboratory Medicine

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