II. Negative

  1. Normal

III. Positive (Percentage refers to sensitivity)

  1. Localized Scleroderma or CREST Syndrome (22-36%)
  2. Associated with pulmonary involvement
  3. Also seen with Raynaud's Phenomenon

IV. References

  1. Gladman in Klippel (1997) Rheumatic Diseases p. 255-6
  2. Peng in Ruddy (2001) Kelley's Rheumatology, p. 161-72
  3. Callegari (1995) Postgrad Med, 97(4):65-74 [PubMed]
  4. Lane (2002) Am Fam Physician 65(6):1073-80 [PubMed]

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Ontology: Antibody to centromere measurement (C0201361)

Concepts Laboratory Procedure (T059)
SnomedCT 143292008, 165906001, 43872009
English Centromere antibody level, Centromere antibody level (procedure), Antibody to centromere measurement, Antibody to centromere measurement (procedure)
Spanish medición de anticuerpos anti - centrómero (procedimiento), medición de anticuerpos anti - centrómero

Ontology: Centromere antibody (C0236514)

Concepts Amino Acid, Peptide, or Protein (T116) , Immunologic Factor (T129)
SnomedCT 12343002, 121132002
LNC LP37577-1, MTHU006229
Spanish anticuerpo anti - centrómero, Anticuerpos anti-centrómeros, anticuerpo anti centrómero (sustancia), anticuerpo anti centrómero, anticuerpo anti - centrómero (sustancia), anticuerpo anticentromérico, anticuerpo anticentrómero (sustancia), anticuerpo anticentrómero
English anti centromere antibody, antibodies centromere, centromere ab, centromere antibody, Anti centromere antibody (substance), Centromere Ab, Centromere Antibody, Anti-Centromere Antibody, Anti centromere antibody, Centromere antibody (substance), Centromere antibody, Anti-centromere antibody, Anti-centromere antibody (substance)
Portuguese Anticorpo anti-centrómero
Dutch anticentromeer-antistof
German Anti-Zentromer-Antikoerper
Hungarian Anti-centroméra antitest
Czech Protilátka proti centromerám
Italian Anticorpi anti centromero
Japanese コウセントロメアコウタイ, 抗セントロメア抗体
French Anticorps anti-centromère