II. Indications
- Start prior to conception of pregnancy
III. Preparations: Key components (Higher doses than standard Vitamins)
-
Folate 400 mcg or 600 Dietary Folate Equivalents or DFE (See Folic Acid for references)
- Dose is higher if increased risk
- Folate 4000 mcg started 3 months before pregnancy (continue for first trimester)
- Prior Neural Tube Defect
- Use of Valproate or Carbamazepine
- Folate 800 mcg daily (1200 Dietary Folate Equivalents or DFE)
- Anti-epileptic drugs other than Valproate or Carbamazepine
- Folate 4000 mcg started 3 months before pregnancy (continue for first trimester)
- Most important component in Prenatal Vitamins
- Reduces Neural Tube Defects by 50% at conception
- Reduced fetal risk of Cleft Lip and Palate by 25-50%
- Reduces conotruncal heart defects by 43%
- Dose is higher if increased risk
-
Calcium 250 mg
- Diet needs supply 750 mg/day to total 1000 mg/day
- See Calcium Supplementation
-
Iron Supplementation (27 to 30 mg elemental iron)
- Higher iron contents are not well absorbed
- Iodine 150 mcg
IV. Preparations: Other Components
- Magnesium Supplementation (320 mg Magnesium)
- Vitamin C 65 mg
-
Zinc 25 mg (See Zinc for references)
- Increases birth weight and Head Circumference
- Results in birth at later Gestational age
- Results in shorter hospital stay
-
Vitamin A 800 mcg (8,000 IU)
- Should not exceed 1000 mcg (10,000 IU)
- Teratogen at higher doses
- Vitamin D 10 mcg
- Vitamin E 10 mcg
- B Vitamins
- Vitamin B6 2.2 mcg
- Thiamine
- Riboflavin
V. Non-Vitamin Components
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Related Studies
| prenatal vitamin (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| PRENATAL VITAMIN PLUS LOW IRON | Generic | $0.12 each |