II. Definition
- Congenital syndrome due to in-utero Phenytoin exposure
III. Epidemiology
- Incidence: <10% of exposed fetuses
IV. Signs
- Microcephaly
- Growth Delay
- Mental Retardation and Developmental Delay
- Craniofacial dysmorphic features
- Flat Nasal Bridge
- Epicanthic folds
- Prominent upper lip over wide mouth
- Distinguishing characteristics
- Nail and distal phalanx hypoplasia
- Hypertelorism
V. Differential Diagnosis
VI. References
- Gabbe (2002) Obstetrics, Churchill, p. 225
- Ellenhorn (1997) Medical Toxicology, Williams, p. 606