Orbital Separation

Aka: Orbital Separation, Hypertelorism, Hypotelorism

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II. Definitions

  1. Hypertelorism
    1. Excessive Orbital Separation (increased space between the eyes)
    2. Results from overdeveloped sphenoid lesser wings
  2. Hypotelorism
    1. Decreased oribtal separation (decreased space between the eyes)

III. Causes: Hypertelorism (increased spacing between the eyes) examples

  1. Apert syndrome
  2. Trisomy 18 (Edwards Syndrome)
  3. Basal Cell Nevus Syndrome
  4. DiGeorge Syndrome
  5. Neurofibromatosis 1
  6. Noonan Syndrome
  7. Zellweger Syndrome
  8. Pierre Robin syndrome

IV. Causes: Hypotelorism (decreased spacing between the eyes) examples

  1. Fetal Alcohol Syndrome
  2. Fragile X Syndrome

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