Multinodular Goiter

Aka: Multinodular Goiter, Toxic Multinodular Goiter, Non-Toxic Multinodular Goiter

advertisement

II. Epidemiology

  1. Toxic Multinodular Goiter is second most common cause of Hyperthyroidism in U.S. (5% of cases)

III. Risk Factors

  1. Diets deficient in Iodine (esp. elderly)

IV. Causes

  1. Simple Goiter develops into Multinodular Goiter

V. Types

  1. Non-Toxic Multinodular Goiter
  2. Toxic Multinodular Goiter (50%)
    1. Increase in clonogenic cells with TSH receptor mutation (somatic activating)
    2. Results in Thyrotoxicosis

VI. Differential Diagnosis

  1. Thyroid Cancer

VII. Symptoms

  1. Dysphagia
  2. Choking Sensation

VIII. Signs

  1. Markedly enlarged nodular Thyroid
  2. Stridor

IX. Complications

  1. Toxic Multinodular Goiter (Thyrotoxicosis)
    1. Cardiovascular complications
      1. Atrial Fibrillation
      2. Tachycardia
      3. Congestive Heart Failure
    2. No Ophthalmopathy (Proptosis and stare)
    3. No Dermopathy
  2. Both Toxic and Non-Toxic Multinodular Goiter
    1. Superior Vena Cava Syndrome
      1. Results from thoracic outlet obstruction

Images: Related links to external sites (from Bing)

These images are a random sampling from a Bing search on the term "Multinodular Goiter." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images

Related Studies

Related Topics in Thyroid Disease

advertisement