II. Epidemiology
- Onset as early as age 18 months
III. Pathophysiology
- Benign self-limited cause of Precocious Puberty
IV. Exam
- Examine with girl lying down
- Identify if Breast glandular tissue beneath areola
V. Signs
VII. Imaging
- Bone Age consistent Chronological age
- Ovarian Ultrasound normal
VIII. Labs
- Serum Gonadotropin levels normal
- Serum Estradiol normal
IX. Management
- Reassurance
- Do not biopsy Breast
- Biopsy results in partial Mastectomy
- Further Breast development abnormal post-biopsy
X. Course
- Spontaneous resolution
XI. References
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Related Studies
| Definition (NCI) | Isolated breast development prior to the normal age of pubertal onset in females.(NICHD) |
| Concepts | Finding (T033) |
| ICD10 | E30.8 |
| SnomedCT | 102889008, 190577006 |
| English | Premature thelarche, Premature developmnt of breast, precocious breast development (symptom), premature thelarche, premature thelarche (diagnosis), precocious breast development, precocious thelarche, premature breast development, Premature breast development, Premature thelarche (disorder), Premature Thelarche, Precocious breast development, Precocious thelarche, Premature development of the breasts, Premature breast development at puberty, Premature development of the breasts (finding), precocious; thelarche, premature; thelarche, thelarche; precocious, thelarche; premature |
| Dutch | vroegtijdige thelarche, prematuur; thelarche, thelarche; prematuur, thelarche; vroegtijdigheid, vroegtijdigheid; thelarche |
| French | Thélarche précoce |
| German | vorzeitige Thelarche |
| Italian | Telarca prematuro |
| Portuguese | Telarca prematura |
| Spanish | Telarquia prematura, desarrollo mamario prematuro, desarrollo prematuro de los senos, desarrollo mamario de la pubertad precoz, desarrollo prematuro de las mamas (hallazgo), telarca prematura (hallazgo), desarrollo prematuro de las mamas, telarca prematura, desarrollo mamario de la pubertad prematuro, telarca precoz |
| Japanese | 早発乳房発育開始, ｿｳﾊﾂﾆｭｳﾎﾞｳﾊﾂｲｸｶｲｼ |
| Czech | Předčasná telarché |
| Hungarian | Korai thelarche |
