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Definition (NCI)
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A generalized state of dysregulated inflammation induced by noninfectious processes. It is characterized by two or more of the following signs and symptoms: fever or hypothermia, increased heart rate, increased respiratory rate, and abnormal white blood cell count.(NICHD)
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Definition (NCI_NCI-GLOSS)
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A serious condition in which there is inflammation throughout the whole body. It may be caused by a severe bacterial infection (sepsis), trauma, or pancreatitis. It is marked by fast heart rate, low blood pressure, low or high body temperature, and low or high white blood cell count. The condition may lead to multiple organ failure and shock.
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Definition (MSH)
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A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
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| Concepts |
Disease or Syndrome
(T047)
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| MSH |
D018746
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| ICD9 |
995.90, 995.9 |
| ICD10 |
R65.10
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| SnomedCT |
238149007, 238150007 |
| English |
Inflammatory Response Syndrome, Systemic, Sepsis Syndromes, Syndrome, Sepsis, Syndromes, Sepsis, Abacteraemic sepsis, SIRS - System inflam resp synd, Systemic inflam response synd, Sepsis Syndrome, SYSTEMIC INFLAMM RESPONSE SYNDROME, INFLAMM RESPONSE SYNDROME SYSTEMIC, SIRS, NOS, systemic inflammatory response syndrome (SIRS) (diagnosis), systemic inflammatory response syndrome (SIRS) due to infectious process (diagnosis), systemic inflammatory response syndrome (SIRS) due to infectious process, systemic inflammatory response syndrome (SIRS), Culture-negative sepsis, Systemic inflammatory response syndrome (SIRS) NOS, Systemic Inflammatory Response Syndrome [Disease/Finding], septic syndrome, syndrome sepsis, sepsis syndrome, Systemic Inflammatory Response Syndrome, Abacteremic sepsis, systemic inflammatory response syndrome, SIRS, SIRS - System inflammatory response syndrome, Sepsis syndrome, Septic syndrome, Systemic inflammatory response syndrome, Sepsis syndrome (disorder), Systemic inflammatory response syndrome (disorder), Systemic inflammatory response syndrome (SIRS), Systemic inflammatory response syndrome, unspecified |
| Italian |
Sindrome da risposta infiammatoria sistemica, Sindrome da sepsi, Sindrome sistemica di risposta infiammatoria, Sindrome settica, SIRS |
| Dutch |
SIRS, sepsissyndroom, systemische ontstekingsreactiesyndroom |
| French |
SIRS (syndrome de réaction inflammatoire systémique), Syndrome septique, SRIS (Systemic Inflammatory Response Syndrome), SRIG, Syndrome de réponse inflammatoire généralisée, Syndrome de réponse systémique inflammatoire, Syndrome de septicémie |
| German |
SIRS, Systemisches inflammatorisches Response-Syndrom, SIRS (Systemisches inflammatorisches Response-Syndrom), Systemisches Inflammationssyndrom, Sepsis-Syndrom, Systemic inflammatory response syndrome |
| Portuguese |
SRIS (Síndrome de Resposta Inflamatória Sistémica), Síndrome Séptica, Síndrome de Resposta Inflamatória Sistêmica, SRIS, Síndrome de Reação Inflamatória Sistêmica, Síndroma de sepsia, Síndrome de resposta inflamatória sistémica, Síndrome Reativa Inflamatória Sistêmica |
| Spanish |
SIRS, Síndrome Séptico, Síndrome de Respuesta Inflamatoria Sistémica, SRIS, síndrome de respuesta inflamatoria sistémica (trastorno), síndrome de respuesta inflamatoria sistémica, síndrome séptico (trastorno), síndrome séptico, Síndrome de respuesta inflamatoria sistémica, Síndrome séptico |
| Japanese |
ＳＩＲＳ, ｾﾞﾝｼﾝｾｲｴﾝｼｮｳﾊﾝﾉｳｼｮｳｺｳｸﾞﾝ, SIRS, ﾊｲｹﾂｼｮｳｼｮｳｺｳｸﾞﾝ, 炎症性反応症候群-全身性, 敗血症症候群, 全身性炎症反応症候群, 全身性炎症性反応症候群, 炎症反応症候群-全身性 |
| Swedish |
Systemisk inflammatorisk respons syndrom
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| Finnish |
Systeeminen tulehduksellinen vasteoireyhtymä
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| Russian |
SISTEMNOI VOSPALITEL'NOI REAKTSII SINDROM, SEPTICHESKII SINDROM, VOSPALITEL'NOI SISTEMNOI REAKTSII SINDROM, СЕПТИЧЕСКИЙ СИНДРОМ, СИСТЕМНОЙ ВОСПАЛИТЕЛЬНОЙ РЕАКЦИИ СИНДРОМ, ВОСПАЛИТЕЛЬНОЙ СИСТЕМНОЙ РЕАКЦИИ СИНДРОМ |
| Czech |
syndrom systémové zánětlivé odpovědi, sepse - syndrom, Syndrom systémové zánětlivé odpovědi, Septický syndrom, SIRS |
| Korean |
상세불명의 전신 염증성 반응 증후군, 전신 염증성 반응 증후군 |
| Polish |
Zespół uogólnionej odpowiedzi zapalnej, Zespół odpowiedzi ogólnoustrojowej na zakażenie, Zespół septyczny, Zespół posocznicowy, Systemowa odpowiedź zapalna, SIRS |
| Hungarian |
Systemás gyulladásos reakció syndroma, sepsis syndroma, SIRS (Systemic inflammatory response syndrome) |
| Norwegian |
Systemisk inflammatorisk respons-syndrom, SIRS |
| Croatian |
Sindrom sustavnog upalnog odgovora
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