II. Lab: Normal
- Range: 50-350 mg/dl
- Varies by age
III. Physiology
IV. Causes: Increased IgA
- Lymphoproliferative disorders (e.g. Multiple Myeloma)
- Berger's Disease (IgA nephropathy)
- Chronic infection
- Autoimmune disorders
- Liver disease (e.g. Portal Cirrhosis)
- Henoch Schonlein Purpura
V. Causes: Decreased IgA
- IgA Hypogammaglobulinemia
- Protein losing Enteropathy
- Hereditary Ataxia and Telangiectasia
- Nephrotic Syndrome
VI. References
- Bakerman (1984) ABCs of Lab Data, p. 252-3
- Immunoglobulin M (IgM)
-
Immunoglobulin E (IgE)
- Long stem (Fc) monomeric Antibody with Molecular weight 180,000 dalton
- Serum Half-Life of 2.5 days
- Reacts to allergans (Type 1 Hypersensitivity) and Parasitic Infections
- Immunoglobulin D (IgD)
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Related Studies
| Definition (MSH) | Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions. |
| Definition (CSP) | predominant immunoglobulin in seromucous secretions such as saliva, colostrum, milk, tracheobronchial and genitourinary secretions. |
| Concepts | Amino Acid, Peptide, or Protein (T116) , Immunologic Factor (T129) |
| MSH | D007070 |
| SnomedCT | 143330004, 165942009, 46046006 |
| LNC | LP14669-3, MTHU005223 |
| English | IgA, Immunoglobulin A, Immunoglobulin A [Chemical/Ingredient], immunoglobulin a, immunoglobulin a (IgA), immu globulin,alpha (IgA), Immunoglobulin A (procedure), Immunoglobulin A (substance), Immunoglobulin IgA, Immunoglobulin IgA (substance), immunoglobulin A, IgA - Immunoglobulin A, Immunoglobulin IgA, NOS |
| Swedish | Immunglobulin A |
| Czech | imunoglobulin A, IgA |
| Finnish | Immunoglobuliini A |
| Russian | IMMUNOGLOBULIN A, IGA, ИММУНОГЛОБУЛИН A |
| Italian | IgA, Immunoglobulina A |
| Croatian | IMUNOGLOBULIN A, IgA |
| Polish | Immunoglobulina A |
| Spanish | Inmunoglobulinas A, inmunoglobulina IgA (sustancia), inmunoglobulina IgA, inmunoglobulina A (sustancia), inmunoglobulina A, IgA, Inmunoglobulina A |
| Portuguese | Imunoglobulinas A, IgA, Imunoglobulina A |
| French | IgA, Immunoglobuline A |
| German | IgA, Immunglobulin A |
