II. Epidemiology

  1. Incidence: Up to 90% of pregnant women by third trimester

III. Risk Factors

  1. Younger age
  2. Fetal Macrosomia
  3. Obesity (higher prepregnancy BMI)
  4. Family History
  5. Non-caucasian

IV. Physiology

  1. Related to Stretching and skin distention with pregnancy
    1. Deep Collagen deposits break apart
  2. Also associated with increased ACTH secretion and other hormonal changes (Estrogen, relaxin)
    1. Affects connective tissue

V. Signs

  1. Red, pink, or purple depressed atrophic bands, streaks associated with skin distention
  2. Most commonly develop in third trimester
  3. Distribution (occurs in areas of higher fat)
    1. Abdomen
    2. Buttocks
    3. Breasts
    4. Thighs
    5. Arms
  4. Regress after delivery
    1. Residual white streaks remain (Striae Albicantes)

VI. Management: Antepartum

  1. Minimal evidence of benefit of any topical in pregnancy
  2. Combine topical agents with daily Skin Massage of the involved regions
  3. Topical agents that have used include cocoa butter, Vitamin E, olive oil, almond oil and aloe vera
  4. Combination products with possible benefit
    1. Tocopherol, Fatty Acids, panthenol, hyaluronic acid
    2. Centella asiatica, alpha-tocopherol, Collagen-elastin
      1. Unclear safety in pregnancy

VII. Management: Postpartum

  1. Typical course is for striae to fade postpartum
  2. Topical Retin A
    1. Indicated if striae in early stages (still red)
    2. May reduce residual changes
    3. Do not use concurrently in pregnancy or Lactation
    4. Systemic Retinoids have been used
  3. Other dermatologic procedures
    1. Pulsed dye laser at 585 nm
    2. Microdermabrasion
    3. Radiofrequency
    4. Microneedling

Images: Related links to external sites (from Bing)

Related Studies

Ontology: Striae gravidarum (C0344310)

Definition (NCI) The visible, linear scarring in the dermis, predominantly of the abdomen due to the stretching of tissue and related hormonal changes during pregnancy.
Concepts Acquired Abnormality (T020)
SnomedCT 271674009, 47212006
English Stretch marks, Striae gravidarum, stretch marks, stretch mark, striae gravidarum, Pregnancy Stretch Mark, Stretch Marks, Striae gravidarum (disorder)
Spanish estrías del embarazo (trastorno), estrías del embarazo, estrías gravídicas

Ontology: striae; albicantes (C1410266)

Concepts Acquired Abnormality (T020)
English striae; albicantes
Dutch striae; albicantes