II. Epidemiology
- Incidence: 90% of pregnant women by third trimester
III. Risk Factors
- Fetal Macrosomia
- Obesity
- Family History
- Non-caucasian
IV. Physiology
- Related to Stretching with pregnancy
- Deep collagen deposits break apart
- Also associated with increased ACTH secretion
- Affects connective tissue
V. Signs
VI. Management: Antepartum
- Minimal evidence of benefit of any topical in pregnancy
- Combination products with possible benefit
- Tocopherol, Fatty Acids, panthenol, hyaluronic acid
- Centella asiatica, alpha-tocopherol, collagen-elastin
- Unclear safety in pregnancy
