Pruritus in Pregnancy

Aka: Pruritus in Pregnancy, Pregnancy Related Pruritus, Pruritus gravidarum, Prurigo gravidarum

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II. Causes

  1. See Pruritus Causes
  2. Pruritic Urticarial Papules and Plaques of Pregnancy
    1. Common, intense Pruritus involving Abdomen
    2. May spread to thighs, buttocks, Breasts and arms
  3. Prurigo of Pregnancy (Common)
    1. Onset in second-half of pregnancy
    2. Papules and Nodules over arms and Abdomen
    3. Associated with Atopic Dermatitis
  4. Herpes Gestationis or Pemphigoid Gestationis (uncommon)
    1. Autoimmune disorder with Grave's Disease association
    2. Occurs in second-half of pregnancy
    3. Vesicles and bullae form on Abdomen, extremities
  5. Intrahepatic Cholestasis of Pregnancy (Common)
    1. No Jaundice in mild form (Prurigo gravidarum)
    2. Trunk and extremity itching without rash
    3. Occurs in third trimester and resolves with delivery
  6. Pruritic Folliculitis of Pregnancy (uncommon)
    1. Prurigo of Pregnancy variant
    2. Pruritus is very mild (not a key feature)
    3. Onset in second half of pregnancy
    4. Erythematous follicular Papules over trunk
    5. Lesions spread to extremities
  7. Non-Primary Pruritic Conditions
    1. Atopic Dermatitis
    2. Contact Dermatitis

III. Management

  1. See Nonspecific Management of Pruritus

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