II. Pathophysiology
- Atopic Eruption of Pregnancy is a collection of immunologic-induced Pruritic Conditions
III. Causes: Atopic Eruption of Pregnancy
- See Atopic Eruption of Pregnancy
-
Prurigo of Pregnancy (Common)
- Onset in second-half of pregnancy
- Erythematous Papules and Nodules over extensor arms and Abdomen
- Associated with Atopic Dermatitis
-
Eczema of Pregnancy or Atopic Dermatitis of Pregnancy (common)
- Pruritic Eczematous Dermatitis affecting the face, chest and flexor extremity surface
-
Pruritic Folliculitis of Pregnancy (uncommon)
- Prurigo of Pregnancy variant
- Pruritus is very mild (not a key feature)
- Onset in second half of pregnancy and resolves postpartum
- Diffuse erythematous follicular Papules over trunk (Abdomen, chest, back)
- Lesions spread to extremities (esp. arms)
IV. Differential Diagnosis: Pruritus in Pregnancy
- See Pruritus Causes
- See Contact Dermatitis
- Pruritic Urticarial Papules and Plaques of Pregnancy (Polymorphic Eruption of Pregnancy)
-
Herpes Gestationis or Pemphigoid Gestationis (uncommon)
- Autoimmune disorder with Grave's Disease association
- Occurs in second-half of pregnancy
- Vesicles and bullae form on Abdomen, extremities
-
Intrahepatic Cholestasis of Pregnancy (Common)
- No Jaundice in mild form (Prurigo gravidarum)
- Trunk and extremity itching without rash
- Occurs in third trimester and resolves with delivery