II. Pathophysiology
- See Blastomycosis
- Caused by Blastomyces dermatidis
- Direct contact of non-intact skin with contaminated soil or decomposing timber
III. Symptoms
- Painful facial lesions (Pustules, ulcers or wart-type lesions)
IV. Signs
- Distribution: Face (esp. eyebrows)
- Verrucous form
- Starts as Papule or Pustule with slow enlargement
- Later, the lesion forms crust with irregular borders
- Secondary Subcutaneous Nodules and micro-abscesses may drain pus
- Ulcerative form
- Ulcerated lesion with sharp border
- Friable red granulation tissue at ulcer base may bleed easily
V. Diagnosis
- Fungal Culture
- Skin biopsy
- Microscopy of purulent discharge (with Potassium Hydroxide or Calcofluor stain)
- Yeast with broad-based buds (8-15 mm diameter)
- Urine Blastomyces Antigen test
- False Positive Histoplasma (high cross reactivity between organisms)
VI. Differential Diagnosis
- Furuncle
- Contagious Ecthyma (Orf)
- Pyogenic Granuloma
- Squamous Cell Carcinoma
VII. Management
- See Blastomycosis
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Related Studies
| Concepts | Disease or Syndrome (T047) |
| ICD10 | B40.3 |
| SnomedCT | 45644002, 187065008 |
| English | Gilchrist's dis affect skin, cutaneous blastomycosis, cutaneous blastomycosis (diagnosis), North American cutaneous blastomycosis (disorder), North American cutaneous blastomycosis, Cutaneous blastomycosis, Gilchrist's disease affecting skin, Cutaneous blastomycosis (disorder), blastomycosis; cutaneous (etiology), blastomycosis; cutaneous (manifestation), blastomycosis; skin (etiology), blastomycosis; skin (manifestation), cutaneous; blastomycotic (etiology), cutaneous; blastomycotic (manifestation), skin; blastomycotic (etiology), skin; blastomycotic (manifestation), North American blastomycotic dermatitis |
| German | Blastomykose der Haut |
| Korean | 피부 분아균증 |
| Spanish | dermatitis blastomicótica norteamericana, blastomicosis cutánea norteamericana (trastorno), blastomicosis cutánea norteamericana, blastomicosis cutánea (trastorno), blastomicosis cutánea, enfermedad de Gilchrist que afecta la piel |
| Dutch | blastomycose; cutaan, blastomycose; huid, cutaan; blastomycose, huid; blastomycose, Cutane blastomycose |
