II. Physiology

  1. See Lipoprotein
  2. Very light (0.93 to 1.006 g/ml), large (30-80 nm) Lipoproteins whose cores are primarily Triglycerides
  3. Surface is a phospholipid and Cholesterol monolayer with embedded apolipoprotein B, E and C
  4. Transport Triglycerides from the liver to Muscle and fat cells
    1. As Triglycerides and Apo C are off-loaded, VLDL becomes intermediate density Lipoprotein (IDL), and then LDL Cholesterol

III. Components

IV. Interpretation: Normal

  1. Normal: 10-31 mg/dl
  2. Calculation
    1. VLDL Cholesterol = (Triglycerides / 5)

V. Causes: Increased

  1. Idiopathic increased hepatic secretion of VLDL
  2. Diabetes Mellitus
  3. Obesity

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Related Studies

Ontology: Very low density lipoprotein (C0023825)

Definition (CSP) class of lipoproteins that transport triglycerides from the intestine and liver to adipose and muscle tissues.
Definition (MSH) A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
Concepts Biologically Active Substance (T123) , Lipid (T119) , Amino Acid, Peptide, or Protein (T116)
MSH D008079
SnomedCT 56516007
LNC LP15710-4, MTHU005012
English Lipoproteins, VLDL, Prebeta Lipoproteins, Very Low Density Lipoproteins, VLDL Lipoproteins, Prebeta-Lipoproteins, very low density lipoprotein, Lipoproteins, Very-Low-Density, Very-Low-Density Lipoproteins, Very low density lipoprotein, Pre beta Lipoproteins, Pre-beta-Lipoproteins, VLDL-Very lo dens lipoprot, Lipoproteins, VLDL [Chemical/Ingredient], very low density lipoprotein (VLDL), very low density lipoproteins, vldl, Lipoprotein.pre-beta, pre-beta Lipoprotein, VLDL, VLDL - Very low density lipoprotein, Pre-beta lipoprotein, Very low density lipoprotein (substance)
French pré-bêta-Lipoprotéines, Lipoprotéines de très basse densité, pré-bêta-Lipoprotéine, VLDL (Very-Low-Density Lipoproteins), Lipoprotéines VLDL, Lipoprotéine de très basse densité
Swedish Lipoproteiner, VLDL
Czech lipoproteiny VLDL
Finnish VLDL-lipoproteiinit
Russian LIPOPROTEIDY, LONP, LIPOPROTEINY, LONP, LIPOPROTEINY OCHEN' NIZKOI PLOTNOSTI, OCHEN' NIZKOI PLOTNOSTI LIPOPROTEINY, PREBETA-LIPOPROTEINY, ЛИПОПРОТЕИДЫ, ЛОНП, ЛИПОПРОТЕИНЫ, ЛОНП, ЛИПОПРОТЕИНЫ ОЧЕНЬ НИЗКОЙ ПЛОТНОСТИ, ОЧЕНЬ НИЗКОЙ ПЛОТНОСТИ ЛИПОПРОТЕИНЫ, ПРЕБЕТА-ЛИПОПРОТЕИНЫ
Croatian LIPOPROTEINI VRLO MALE GUSTOĆE
Polish Lipoproteiny VLDL, Lipoproteidy o bardzo niskiej gęstości, VLDL
Japanese VLDリポ蛋白質, 超低密度リポ蛋白質, VLDLリポ蛋白質, プレベータリポ蛋白質, 超低密度リポタンパク質, 超低比重リポ蛋白質, リポ蛋白質-VLDL, 超低密度リポ蛋白
Spanish lipoproteína de muy baja densidad (sustancia), lipoproteína de muy baja densidad, lipoproteína pre - beta, Lipoproteínas Prebeta, Lipoproteínas VLDL, Lipoproteínas de muy Baja Densidad
German Lipoproteine, VLDL-, Very-Low-Density-Lipoproteine, Lipoproteine, Prä-Beta-, Prä-Beta-Lipoproteine
Italian Lipoproteine VLDL
Portuguese Lipoproteínas VLDL, Pré-beta-Lipoproteínas, Lipoproteínas de Densidade muito Baixa