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Ontology:
Troponin I
(C0077401)
Definition (NCI)
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Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. In the absence of calcium, Troponin I binds actin, inhibits actomyosin ATPase activity, and inhibits F-actin-myosin interactions. The troponin I gene family comprises three isoforms: skeletal TNI-fast, skeletal TNI-slow, and TNI-cardiac. (from OMIM 191044, 191043, 191042 and NCI)
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Definition (MSH)
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One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.
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Concepts |
Biologically Active Substance
(T123)
, Amino Acid, Peptide, or Protein
(T116)
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MSH |
D019210
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SnomedCT |
102683006
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English |
Troponin I, Troponin-I, inhibitory troponin I, TnI, Troponin I [Chemical/Ingredient], tni, troponin-i, troponin i, Inhibitory troponin subunit, Troponin I (substance) |
Swedish |
Troponin I
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Czech |
troponin I
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Finnish |
Troponiini I
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Russian |
TROPONIN I, ТРОПОНИН I |
Japanese |
トロポニンI
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Polish |
Troponina I
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Croatian |
Troponin I
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Spanish |
subunidad de troponina inhibitoria, troponina I (sustancia), troponina I, Troponina I |
French |
Troponine I
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German |
Troponin I
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Italian |
Troponina I
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Portuguese |
Troponina I
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Ontology:
Troponin I measurement
(C0920210)
Definition (NCI)
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The determination of the amount of troponin I present in a blood sample.
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Definition (NCI_CDISC)
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A measurement of the actin binding troponin in a biological specimen.
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Concepts |
Laboratory Procedure
(T059)
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SnomedCT |
121870001
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English |
Troponin I, Troponin I Measurement, troponin i level test, troponin i test, Troponin I measurement, TROPONI, Troponin I measurement (procedure) |
Italian |
Troponina I
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Japanese |
トロポニンI, トロポニンI |
Czech |
Troponin I
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Hungarian |
Troponin I
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Spanish |
medición de troponina I (procedimiento), medición de troponina I, Troponina I |
Portuguese |
Tropoinina I
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Dutch |
troponine-I
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French |
Troponine I
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German |
Troponin I
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