II. Precautions
- Recognize signs of shock early- Tachycardia- See Heart Rate for normal ranges for age
- Early warning sign of shock in most cases
- Cold and tachycardic is shock until proven otherwise
- However can be misleadingly normal in cases of Delayed Tachycardia
 
- Avoid relying on late, unreliable markers of shock- Hemoglobin And Hematocrit may not reflect massive blood loss for hours
- Blood Pressure does not fall until all compensatory mechanisms are overwhelmed
 
 
- Tachycardia
- Promptly identify shock cause- Most cases are Hemorrhagic Shock in the Trauma patient- See Hemorrhagic Shock
- Emergent surgical Consultation
- Paramount to locate and stop the source of bleeding (and replace losses)
 
- Consider other forms of shock- Tension Pneumothorax
- Cardiac Tamponade
- Neurogenic Shock secondary to Spinal Cord Injury (not due to isolated intracranial injury)
 
 
- Most cases are Hemorrhagic Shock in the Trauma patient
III. Indications: Signs of shock
- Mottled or pale color
- Cool skin
- Diminished peripheral pulses
- Delayed capillary pulses despite normal Ambient temp
- Mental status changes
- Oliguria
- Shock may be present despite normal Blood Pressure
IV. Preparations: Available Fluids for Volume Expansion
- Crystalloid Isotonic Solution
- Colloid Solution
- 
                          Blood Products- Inadequate improvement after 2 crystalloid boluses (old recommendation)
- Newer guidelines as of 2013 suggest early transition to replacing blood loss with Blood Products
 
V. Protocol: Fluid Replacement
- See Hemorrhagic Shock
- See precautions above
- Approach- Initial fluid Resuscitation is with crystalloid- Heated crystalloid (to 39 C or 102.2 F) is preferred to prevent Hypothermia
 
- Closely monitor for response to fluid Resuscitation- Rapid and sustained response to fluid bolus (<10-20% blood loss)- Monitor for decompensation (especially if risk of Delayed Tachycardia)
 
- Transient response to fluid bolus (20-40% blood loss, ongoing)- Emergent Blood Transfusion
- Close monitoring for surgical intervention
 
- No response to fluid bolus (>40% blood loss)- Emergent surgical or angiographic intervention
- Emergent Blood Transfusions (assume Massive Hemorrhage)
 
 
- Rapid and sustained response to fluid bolus (<10-20% blood loss)
 
- Initial fluid Resuscitation is with crystalloid
- Initial fluids - Replace first liter with crystalloid- Isotonic crystalloid (Normal Saline and Lactated Ringers are equivalent) is standard of care
- Hypertonic Saline may be used instead (?antiinflammatory) but studies do not support benefit- Bulger (2011) Ann Surg 253(3): 431-41
 
- Do not use dextrose solutions- Induces osmotic diuresis
- Results in Hypokalemia
- Worsens ischemic brain injury
 
 
- Subsequent fluids (after first liter)- Replace blood loss with Packed Red Blood Cells
- Massive Blood Transfusion is typically accompanied by Platelet and Plasma Transfusion
 
- References- Inaba and Herbert in Majoewsky (2013) EM:Rap 13(7): 4
 
VI. Monitoring: General
- See Central Venous Pressure (CVP)
- Inferior Vena Cava Ultrasound for Volume Status
- Reassess systemic perfusion after each bolus- Urinary output- Normal Urine Output is >0.5 ml/kg/h in adults (>1 ml/kg/h in children, >2 ml/kg/h in infants)
 
- Level of Consciousness
- Peripheral perfusion
- Blood Pressure- Do not rely solely on blood presure as a marker of improvement (may simply reflect Vasoconstriction)
 
- Heart Rate
 
- Urinary output
- Move swiftly to replacement of Blood Products if no response to Intravenous Fluids
- Large volume replacement is not a substitute for identifying and stopping active Hemorrhage
VII. Dosing
- Bolus Volumes given rapidly (<20 minutes)- Adult: 1-2 Liter Bolus IV
- Child: 20 ml/kg LR or NS IV or IO- Use 35-50 cc syringe attached to inline 3-way stop-cock
 
 
- Repeat dosing- Assume Hemorrhagic Shock and replace with Blood Products
- May require 2-3 boluses within first hour until Blood Products- Septic Shock is rare in Trauma, but may require 4 boluses in first hour
 
 
VIII. References
- (2012) ATLS Manual, 9th ed, American College of Surgeons
