II. Epidemiology
- May ocur at any age
- Incidence: 1% of newborns (Congenital Sebaceous Hyperplasia)
III. Pathophysiology
- Normal, benign variant of ectopic Sebaceous Gland hyperplasia on Buccal mucosa
- Lesions contain sebaceous lobules
- Lesions are not associated with Hair Follicles
- In newborns, lesions are associated with increased maternal androgen levels
IV. Signs
- Characteristics
- Distribution
- Buccal mucosa
- Vermillion border of lips
- Genital mucosa (older children or adults)
V. Differential Diagnosis
- Bohn Nodule (Epstein's Pearls, Dental Lamina Cysts)
- Neonatal Herpes Simplex
- Mucocele
- Condyloma acuminata
VI. Course
- Congenital Sebaceous Hyperplasia (newborns)
- Resolves by a few weeks of life
VII. References
Images: Related links to external sites (from Bing)
Related Studies
| Concepts | Congenital Abnormality (T019) , Disease or Syndrome (T047) |
| SnomedCT | 201245000, 204637000, 50584008 |
| English | fordyces spots, fordyce's disease, fordyces granules, fordyce disease, fordyce granules, ectopic sebaceous glands, fordyce granule, fordyce's granules, fordyce spot, fordyce spots, fordyces spot, Ectopic sebaceous glands (disorder), Ectopic sebaceous gland tissue, Fordyce granules, Fordyce spots, Fordyce's disease, Ectopic oral sebaceous glands, Ectopic sebaceous glands, Fordyce disease, Fordyce's disease of mouth, Fordyce's granules, Fordyce's disease (disorder), Fordyce, aberrant; sebaceous glands, sebaceous glands; aberrant |
| Czech | Fordyceho skvrny |
| Dutch | vlekken van Fordyce, aberrant; talgklieren, talgklieren; aberrant |
| French | Grains de Fordyce |
| German | Fordyce-Flecken |
| Hungarian | Fordyce foltok |
| Italian | Macchie di Fordyce |
| Spanish | Manchas de Fordyce, enfermedad de Fordyce (trastorno), enfermedad de Fordyce, gránulos de Fordyce, manchas de Fordyce, tejido glandular sebáceo ectópico |
| Japanese | ﾌｫｱﾀﾞｲｽﾊﾝ, フォアダイス斑 |
| Portuguese | Manchas de fordyce |
