II. Epidemiology

  1. Most common in children and young adults

III. Definitions

  1. Mucocele (Mucous Retention Cyst, typically of the lip)
    1. Traumatic rupture of small Salivary Glands with spillage of mucin (typically within the lower lip)
  2. Ranula (Mucocele of the mouth floor)
    1. Mucocele of the oropharyngeal floor
    2. Most often due to submaxillary or Sublingual Gland duct obstruction
    3. Plunging Ranula extends beyond the mylohyoid Muscle

IV. Causes

  1. Local Trauma (e.g. biting lip)

V. Pathophysiology

  1. Results from Traumatic rupture of Salivary Glands
  2. Results in mucin spillage into lower lip

VI. Signs

  1. Benign lesion 1-2 cm diameter
  2. Round, regular, translucent or bluish Nodule
  3. Distribution
    1. Typically occurs on inside of lower lip
    2. May occur in any oral surface with Salivary Glands
  4. Consistency
    1. Early lesions are fluctuant
    2. Later lesions are firm and fibrotic

VII. Differential Diagnosis

  1. Lip Neoplasm
  2. Lip Aneurysm
  3. Dermoid Cyst

VIII. Management

  1. Small Mucoceles resolve spontaneously without treatment
  2. Local treatment techniques
    1. Indicated in lesions that are typical for Mucocele
    2. Anesthesia with Local Lidocaine with Epinephrine at the base of the lesion
    3. Technique 1
      1. Shave the lesion with scalpel, removing the top 50-75% but leaving the base
      2. Obtain Hemostasis
    4. Technique 2
      1. Place 4-0 or 5-0 Nylon Suture through the Mucocele, creating 2 holes in its surface
      2. Tie the Suture and remove in 5-7 days
    5. Other techniques
      1. Cryotherapy
      2. Electrocautery
  3. Surgical excision
    1. Indicated for suspicious lesions (refer to otolaryngology, oral facial surgery or dermatology)
    2. Also excise minor Salivary Glands at Mucocele base
    3. Send for pathology to rule-out neoplasia

IX. References

  1. Warrington (2020) Crit Dec Emerg Med 34(1): 13
  2. Randall (2022) Am Fam Physician 105(4): 369-76 [PubMed]

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Related Studies

Ontology: Mucocele (C0026683)

Definition (MSHCZE) Nahromadění hlenu v určitém prostoru, např. v dutém orgánu. (cit. Velký lékařský slovník online, 2012 http://lekarske.slovniky.cz/ )
Definition (NCI) A mucous containing cyst arising from the minor salivary glands in the oral cavity.
Definition (MSH) A retention cyst of the salivary gland, lacrimal sac, paranasal sinuses, appendix, or gallbladder. (Stedman, 26th ed)
Concepts Anatomical Abnormality (T190)
MSH D009078
SnomedCT 19633006
English Mucocele, Mucoceles, Mucous Cyst, Mucocele [Disease/Finding], mucocele, mucous retention cyst, mucus cyst, mucous cyst, mucinous cyst, mucoceles, Mucocoele, Mucus cyst, Mucinous cyst, Mucous cyst, Mucous retention cyst, Mucous cyst (morphologic abnormality)
Swedish Slemcysta
Finnish Mukoseele
Russian MUKOTSELE, МУКОЦЕЛЕ
Polish Torbiel zastoinowa gruczołów śluzowych, Torbiel śluzowa, Śluzowiak
Czech mukokéla, mukokély, mukokela
Norwegian Slimcyste, Mukocele
Spanish mucocele, quiste de retención mucoso, quiste mucinoso, quiste mucoso (anomalía morfológica), quiste mucoso, Mucocele
French Mucocèle
German Mukozele
Italian Mucocele
Dutch Mucocele, Mucokèle
Portuguese Mucocele

Ontology: Ranula (disorder) (C2242813)

Definition (MSH) A form of retention cyst of the floor of the mouth, usually due to obstruction of the ducts of the submaxillary or sublingual glands, presenting a slowly enlarging painless deep burrowing mucocele of one side of the mouth. It is also called sublingual cyst and sublingual ptyalocele.
Concepts Disease or Syndrome (T047)
MSH D011900
ICD10 K11.6
SnomedCT 155657002, 14919007
English Ranula, Ranulas, Ranula (disorder), ranula (diagnosis), ranula, Ranula [Disease/Finding], Sublingual mucocele, Ranula of floor of mouth, Ranula of salivary gland of floor of mouth, Sublingual cyst
Japanese がま腫, ガマシュ
Swedish Ranula
Czech ranula, Ranula
Finnish Ranula
Russian RANULA, РАНУЛА
Spanish Ránula, quiste sublingual, ránula (trastorno), ránula de la glándula salival del piso de la boca, ránula del piso de la boca, ránula
Portuguese Rânula
Polish Żabka podjęzykowa, Torbiel podjęzykowa
Hungarian Ranula
Norwegian Ranula, Retensjonscyste i munngulv
Dutch ranula, Ranula
French Ranule, Grenouillette sublinguale, Grenouillette, Sialocèle sublingual
German Ranula, Retentionszyste, Mundboden-, Mundbodenretentionszyste
Italian Ranula