II. Epidemiology

  1. Much less common than Leukoplakia
  2. More predictive of neoplasm than Leukoplakia
    1. 90% of early carcinomas appear as Erythroplakia (severe dysplasia, carcinoma in situ or carcinoma)

III. Signs: Erythematous counterpart to Leukoplakia

  1. Red, velvet-like lesion (smooth or pebbly surface)
  2. Speckled Leukoplakia (Erythroleukoplakia) may also be present
    1. White patches on periphery of Erythroplakia

IV. Differential Diagnosis

  1. Epithelial dysplasia
  2. Squamous Cell Carcinoma

V. Management

  1. Biopsy if lesion persists >2 weeks

VI. Prevention

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Ontology: Erythroplasia (C0014818)

Definition (NCI_NCI-GLOSS) An abnormal patch of red tissue that forms on mucous membranes in the mouth and may become cancer. Tobacco (smoking and chewing) and alcohol may increase the risk of erythroplakia.
Definition (NCI) A clinical term that refers to the presence of a red flat and well defined lesion on the oral mucosa that is not caused by trauma, vascular, or inflammatory processes. It is a precancerous condition and is seen more commonly in middle aged or older males. It is associated with tobacco and alcohol consumption. Microscopic examination reveals severe epithelial dysplasia, carcinoma in situ, or invasive squamous cell carcinoma.
Definition (MSH) A condition of the mucous membrane characterized by erythematous papular lesions. (Dorland, 27th ed)
Concepts Disease or Syndrome (T047)
MSH D004919
ICD10 D00-D09
SnomedCT 189208007, 71379006
English Erythroplasia, Erythroplasias, erythroplasia, Erythroplasia [Disease/Finding], erythroplakia, Erythroplakia, Erythroplakia (morphologic abnormality), Erythroplakia, NOS, Erythroplasia, NOS
Japanese 紅色肥厚症, コウショクヒコウショウ
Swedish Erytroplasi
Czech erytroplazie, Erytroplazie
Finnish Erytroplasia
Polish Erytroplazja
Hungarian Erythroplasia
Dutch erytroplasie, Erytroplasie
Norwegian Erytroplasi
Spanish eritroplaquia, eritroplasia (anomalía morfológica), eritroplasia, Eritrodisplasia, Eritroplasia
French Érythroplasie, Érythroplasie de Queyrat, Maladie de Queyrat
German Erythroplasie
Italian Eritroplasia
Portuguese Eritroplasia