II. Epidemiology
- Prevalence: 200,000 in U.S.
- Mortality: 2,000 deaths per year in U.S
III. Pathophysiology
- Fibrotic lung disease secondary to Asbestos inhalation
IV. Symptoms
- Dry, non-productive cough
- Exertional Dyspnea
V. Signs
- Auscultory rales
VI. Imaging
-
Chest XRay
- Interstitial Markings increased (esp. lower lobes)
- Pleural Plaques may be present
- Consider Chest CT
- Interstitial Markings increased as on Chest XRay
- Honeycomb appearance
VII. Diagnostics
-
Pulmonary Function Tests
- Initial
- Decreased DLCO (diffusion capacity)
- Decreased ambulatory Oxygen Saturation
- Later
- Initial
- Lung biopsy
VIII. Differential diagnosis
-
Idiopathic Pulmonary Fibrosis
- IPF is a more rapid progression
- Pulmonary fibrosis due to Collagen vascular disease
IX. Associated conditions
- Pleural Plaques
-
Lung Cancer
- Use high index of suspicion
X. Management
- No specific management
- Tobacco Cessation
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Definition (MSH) | A form of pneumoconiosis caused by inhalation of asbestos fibers which elicit potent inflammatory responses in the parenchyma of the lung. The disease is characterized by interstitial fibrosis of the lung, varying from scattered sites to extensive scarring of the alveolar interstitium. |
Definition (NCI_NCI-GLOSS) | A lung disease caused by breathing in particles of asbestos (a group of minerals that take the form of tiny fibers). Symptoms include coughing, trouble breathing, and chest pain caused by scarring and permanent damage to lung tissue. Asbestosis increases the risk of lung cancer and malignant mesothelioma (cancer found in the lining of the lungs, chest, or abdomen). |
Definition (NCI) | A lung disorder caused by inhalation of asbestos fibers. It results in fibrosis of the lung parenchyma. Signs and symptoms include coughing, shortness of breath and chest pain. |
Concepts | Disease or Syndrome (T047) |
MSH | D001195 |
ICD9 | 501 |
ICD10 | J61 |
SnomedCT | 266400008, 196006003, 155589004, 22607003 |
English | Asbestoses, Asbestosis, ASBESTOSIS, Asbestosis NOS, PULMONARY ASBESTOSIS, asbestosis, asbestosis (diagnosis), Asbestosis [Disease/Finding], pulmonary asbestosis, asbestoses, Asbestosis NOS (disorder), Amianthosis, Asbestos pneumoconiosis, Pulmonary asbestosis, Asbestosis (disorder) |
French | ASBESTOSE, Asbestose |
Portuguese | ASBESTOSE, Asbestose |
Japanese | 石綿肺症, セキメンハイショウ |
Swedish | Asbestos |
Czech | azbestóza, Azbestóza |
Finnish | Asbestoosi |
Russian | ASBESTOZ, АСБЕСТОЗ |
Croatian | AZBESTOZA |
Polish | Azbestoza, Pylica azbestowa |
Hungarian | Asbestosis |
Spanish | asbestosis, SAI (trastorno), asbestosis, SAI, amiantosis, asbestosis (trastorno), asbestosis, neumoconiosis por amianto, Asbestosis |
Norwegian | Asbestose |
Dutch | asbestose, Asbestose |
German | Asbestose |
Italian | Asbestosi |