II. Definition
- Asbestos-related Lung Cancer
III. Risk Factors
- Asbestos Exposure (even minor exposure)
- Tobacco Abuse
IV. Epidemiology
- Incidence: 2000 new cases in U.S. per year
V. Symptoms
VI. Imaging
-
Chest XRay
- Unilateral Pleural Effusion
-
Chest CT
- Pleura may appear irregular
VII. Presentations
- Vague cardiopulmonary symptoms
- Superior Vena Cava Syndrome
- Horner's Syndrome
- Dysphagia
VIII. Managament
- Palliative radiation
- No protocol improves survival
IX. Prognosis
- Uniformly fatal
- Median survival: 6-18 months from diagnosis
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Definition (CHV) | a benign or malignant tumor affecting the lining of the chest or abdomen |
Definition (CHV) | a benign or malignant tumor affecting the lining of the chest or abdomen |
Definition (MEDLINEPLUS) |
The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma is a tumor of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs. It can be benign (not cancer) or malignant (cancer.) Malignant mesothelioma is a rare but serious type of cancer. Most people who get it have worked on jobs where they inhaled asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form. Symptoms include
Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. Your doctor uses imaging tests and a biopsy to make the diagnosis. Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment may include surgery, radiation, and/or chemotherapy. NIH: National Cancer Institute |
Definition (NCI_NCI-GLOSS) | A benign (noncancerous) or malignant (cancerous) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma. |
Definition (NCI) | A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos. |
Definition (NCI_CDISC) | A neoplasm originating from mesothelial cells of the pleura or peritoneum, for which the malignancy status has not been established. |
Definition (CSP) | malignant tumor derived from mesothelial tissues of peritoneum, pleura, and pericardium. |
Definition (MSH) | A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed) |
Concepts | Neoplastic Process (T191) |
MSH | D008654 |
ICD10 | C45 , C45.9 |
SnomedCT | 154491004, 187873000, 190110008, 189837000, 115232000, 62064005 |
English | Mesotheliomas, Mesothelioma, unspecified, [X]Mesothelioma, unspecified, [M]Mesothelioma, unspecified, Mesothelioma [Disease/Finding], mesothelioma, mesotheliomas, Mesothelioma (disorder), [X]Mesothelioma, unspecified (disorder), [M]Mesothelioma, unspecified (morphologic abnormality), MESOTHELIOMA, UNDETERMINED, Mesothelioma, mesothelioma; unspecified site, Mesothelioma, NOS |
Italian | Mesoteliomi, Mesotelioma |
Japanese | 中皮腫, チュウヒシュ |
Swedish | Mesoteliom |
Czech | mezoteliom, Mezoteliomy, Mezoteliom |
Finnish | Mesoteliooma |
Russian | MEZOTELIOMA, МЕЗОТЕЛИОМА |
German | Mesotheliom, nicht naeher bezeichnet, Mesotheliome, Mesotheliom |
Korean | 상세불명의 중피종, 중피종 |
Polish | Międzybłoniak |
Hungarian | Mesothelioma, Mesotheliomák |
Norwegian | Mesoteliom |
Spanish | [M]mesotelioma, no especificado (anomalía morfológica), [X]mesotelioma, no especificado (trastorno), [X]mesotelioma, no especificado, [M]mesotelioma, no especificado, mesotelioma, SAI, mesotelioma, Mesoteliomas, Mesotelioma |
Dutch | mesothelioom; niet gespecificeerde lokalisatie, Mesothelioom, niet gespecificeerd, mesotheliomen, mesothelioom, Mesothelioom |
Portuguese | Mesoteliomas, Mesotelioma |
French | Mésothéliomes, Mésothéliome |
Ontology: Diffuse malignant mesothelioma (C0392400)
Definition (NCI) | A malignant neoplasm that arises from the mesothelial cells. Histologic variants include biphasic, epithelioid, sarcomatoid, and desmoplastic mesothelioma. |
Concepts | Neoplastic Process (T191) |
English | diffuse malignant mesothelioma, dmm, diffuse malignant mesothelioma (DMM), diffuse malignant mesotheliomas, Diffuse malignant mesothelioma, Diffuse Malignant Mesothelioma, Malignant Diffuse Mesothelioma |