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Definition (NCI)
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Breast cancer type 2 susceptibility protein (3418 aa, ~384 kDa) is encoded by the human BRCA2 gene. This protein plays a role in both cell cycle regulation and DNA repair.
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Definition (MSH)
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A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
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| Concepts |
Biologically Active Substance
(T123)
, Amino Acid, Peptide, or Protein
(T116)
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| MSH |
D024682
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| SnomedCT |
405828007
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| French |
Protéine du groupe de complémentation D1 de l'anémie de Fanconi, Protéine BRCA-2, Protéine FANC-D-1, Protéine du groupe D-1 de l'anémie de Fanconi, Protéine du groupe D1 de l'anémie de Fanconi, Protéine BRCA2, Protéine du groupe D-1 de la maladie de Fanconi, Protéine FANC-D1, Protéine FANCD1, Protéine du groupe D1 de la maladie de Fanconi |
| Swedish |
BRCA2-protein
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| English |
BRCA PROTEIN 002, FANCONI ANEMIA COMPLEMENTATION GROUP D 01 PROTEIN, Breast Cancer Type 2 Susceptibility Protein, BRCA2 Protein [Chemical/Ingredient], BRCA2 Gene Product, Breast Cancer 2 Gene Product, BRCA2 gene product, Breast cancer type 2 susceptibility protein (substance), Breast cancer type 2 susceptibility protein, BRCA2 Protein, BRCA2, FANCB, FANCD1, Breast Cancer 2, Early Onset Protein, Breast Cancer 2 Protein, FANCD1 Protein, Fanconi Anemia Complementation Group D1 Protein, Fanconi Anemia Group D1 Complementing Protein, Fanconi Anemia Group D1 Protein |
| Czech |
protein BRCA2
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| Finnish |
BRCA2-proteiini
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| Russian |
BRCA2 BELOK, MOLOCHNOI ZHELEZY RAKA GENA 2 BELOK, BRCA2 БЕЛОК, МОЛОЧНОЙ ЖЕЛЕЗЫ РАКА ГЕНА 2 БЕЛОК |
| Japanese |
BRCA2遺伝子産物, ファンコニー貧血相補群D1蛋白質, Fanconi貧血相補群D1蛋白質, BRCA2蛋白質 |
| Italian |
Proteina FANCD1, Prodotto genico BRCA2, Proteina BRCA2 |
| German |
BRCA PROTEIN 002, BRUSTKREBS GENPRODUKT 02, BRCA2-Protein, Brustkrebs-2-Genprodukt |
| Polish |
Białko BRCA2
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| Croatian |
Protein BRCA2
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| Spanish |
proteína de susceptibilidad al cáncer de mama tipo 2 (sustancia), proteína de susceptibilidad al cáncer de mama tipo 2, Producto del Gen 2 del Cáncer de Mama, Proteína BRCA2, Proteína del Grupo de Complementación D1 de la Anemia de Fanconi |
| Portuguese |
Produto do Gene do Câncer de Mama 2, Proteína BRCA2, Proteína do Grupo de Complementação D1 da Anemia de Fanconi |
