Definition (NCI)
|
Breast cancer type 1 susceptibility protein (1863 aa, ~208 kDa) is encoded by the human BRCA1 gene. This protein plays a role in both the maintenance of DNA and the mediation of ubiquitin E3 ligase activity.
|
Definition (MSH)
|
The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)
|
Concepts |
Biologically Active Substance
(T123)
, Amino Acid, Peptide, or Protein
(T116)
|
MSH |
D019313
|
SnomedCT |
405827002
|
English |
BRCA1 Gene Product, BRCA1 Protein, BRCA PROTEIN 001, BRCA GENE PRODUCT 001, RING Finger Protein 53, Breast Cancer Type 1 Susceptibility Protein, EC6.3.2.-, BRCA1 Protein [Chemical/Ingredient], Breast Cancer 1 Gene Product, BRCA1 gene product, Breast cancer type 1 susceptibility protein (substance), Breast cancer type 1 susceptibility protein, BRCA1, Breast Cancer 1, Early Onset Protein, Breast-Ovarian Cancer Protein, Breast Cancer 1 Protein |
Swedish |
BRCA1-protein
|
Czech |
protein BRCA1
|
Finnish |
BRCA1-proteiini
|
Russian |
BRCA1 BELOK, BRCA1 GENA PRODUKT, BRCA1 БЕЛОК, BRCA1 ГЕНА ПРОДУКТ |
Japanese |
BRCA1遣伝子産物, BRCA1蛋白質, BRCA1タンパク質 |
German |
BRCA GEN PRODUKT 001, BRUSTKREBS GENPRODUKT 01, BRCA PROTEIN 001, BRCA1-Genprodukt, BRCA1-Protein, Brustkrebs-1-Genprodukt |
Polish |
Produkt genu BRCA1, Białko BRCA1 |
Croatian |
Protein BRCA1
|
Spanish |
proteína de susceptibilidad al cáncer de mama tipo 1 (sustancia), proteína de susceptibilidad al cáncer de mama tipo 1, Producto del Gen BRCA1, Producto del Gen 1 del Cáncer de Mama, Proteína BRCA1 |
French |
Produit gène BRCA1, Protéine BRCA1 |
Italian |
Proteina BRCA1
|
Portuguese |
Produto do Gene BRCA1, Produto do Gene do Câncer da Mama 1, Proteína BRCA1 |