II. Definitions
- Orbicularis Paralysis
- Orbicularis Oculi Muscle paralysis
- Results in failure of Eyelid closure
- Lid Lag (Von Graefe Sign)
- Lid Retraction (Dalrymple Sign)
III. Pathophysiology
- Lid Lag and Lid Retraction
- Results from sympathetic hyperactivity (typically due to Hyperthyroidism)
- Increased contractions of the Muller Muscle (Eyelid elevator)
IV. Causes: Unilateral
V. Causes: Bilateral
- Lid spasm from sympathetic stimulation
-
Exophthalmos (Proptosis)
- Bilateral in Graves Disease
- Unilateral with orbital masses, Cavernous Sinus Thrombosis
-
Hyperthyroidism
- Any Hyperthyroidism (e.g. Thyroiditis) may cause Lid Lag or Lid Retraction
- Graves Disease also causes Exophthalmos (as above)
VI. Complications
- Corneal Injury due to lack of protection, dryness
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Related Studies
| Concepts | Sign or Symptom (T184) |
| ICD10 | H02.53 |
| SnomedCT | 193948003, 267737009, 155180006, 89893000 |
| Italian | Ritardo palpebrale |
| Japanese | 閉眼遅延, ﾍｲｶﾞﾝﾁｴﾝ |
| English | lid lag, lid lag (physical finding), Eyelid lag, eyelid lag, Lag, lid, Lid lag, Lid lag (finding) |
| Czech | Zaostávání očního víčka |
| Hungarian | Graefe-tünet |
| Spanish | retraso del parpadeo (hallazgo), retraso del parpadeo, Asinergia palpebral |
| Portuguese | Pálpebra preguiçosa |
| Dutch | ooglidvertraging |
| French | Asynergie oculo-palpébrale |
| German | Graefe-Zeichen |
Ontology: Retraction of eyelid (C0234665)
| Concepts | Sign or Symptom (T184) |
| ICD10 | H02.53 |
| SnomedCT | 193948003, 14520009, 43854003 |
| English | EYELID RETRACTION, eyelid retraction, eyelid retraction (physical finding), Eyelid retraction, lid retraction, Lid retraction, Lid retraction (finding), Retraction of eyelid (disorder), Retraction of eyelid, eyelid; retraction, retraction; eyelid, Retraction of eyelid, NOS |
| Italian | Retrazione della palpebra |
| Japanese | 眼瞼後退, ｶﾞﾝｹﾝｺｳﾀｲ |
| German | AUGENLIDRETRAKTION, Augenlidretraktion |
| Spanish | PARPADO, RETRACCION, retracción de los párpados (hallazgo), retracción de los párpados, retracción del párpado (trastorno), retracción del párpado, Retracción del párpado |
| Portuguese | RETRACAO DA PALPEBRA, Retracção palpebral |
| French | RETRACTION DE LA PAUPIERE, Rétraction de la paupière |
| Czech | Retrakce očního víčka |
| Hungarian | Szemhéj retractio |
| Dutch | ooglid; retractie, retractie; ooglid, ooglidretractie |
Ontology: Von Graefe sign (C0278217)
| Concepts | Sign or Symptom (T184) |
| SnomedCT | 11180004, 89893000 |
| Dutch | symptoom van Von Graefe |
| French | Signe de Graefe |
| German | Zurueckbleiben des oberen Augenlids |
| Italian | Segno di Graefe |
| Portuguese | Sinal de Graefe |
| Spanish | Signo de Graefe, signo de von Graefe, signo de von Graefe (hallazgo), signo de Graefe |
| Japanese | グレーフェ徴候, ｸﾞﾚｰﾌｪﾁｮｳｺｳ |
| Czech | Graefeho příznak |
| Hungarian | Graefe tünet |
| English | Von Graefe's sign (finding), Graefe's sign, Von Graefe's sign, Graefe sign, Von Graefe sign |
