II. Causes: Bilateral Eyelid Inflammation

  1. Eyelid Contact Dermatitis (marked edema with erythema)
  2. Atopic Dermatitis (erythema, fine scale and lichenification)
    1. Typical involvement for adult Atopic Dermatitis
  3. Autoimmune Conditions
    1. Dermatomyositis (Heliotrope rash)
    2. Discoid Lupus (Localized Eyelid lesion)
  4. Blepharitis
  5. Seborrhea
  6. Rosacea
  7. Pediculosis Ciliaris (eyelash lice)
  8. Systemic conditions with Eyelid Edema
    1. Angioedema
    2. Congestive Heart Failure
    3. Hypothyroidism
    4. Renal Failure

III. Causes: Unilateral Eyelid Inflammation

  1. See bilateral causes above (may be asymmetric)
  2. Herpes Simplex
  3. Herpes Zoster Ophthalmicus
  4. Hordeolum (stye) or Chalazion
  5. Periorbital Cellulitis or Preseptal Cellulitis
  6. Malignancy
    1. Basal Cell Carcinoma (90% of Eyelid malignancies)
    2. Squamous Cell Carcinoma (5-10% of Eyelid malignancies)
    3. Sebaceous carcinoma (<5% of Eyelid malignancies)
    4. Cutaneous T Cell Lymphoma

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