II. Epidemiology
- Onset in up to 20% of newborns
III. Pathophysiology
- Maternal androgenic Hormones stimulate the newborns Sebaceous Glands
- Resolves without scarring when maternal Hormones wane after 3-4 months
IV. Signs
V. Differential Diagnosis
- Neonatal Pustules and Vessicles
- Infantile Acne
- Onset at >6 weeks of life and persists for 6 to 12 months
- More inflammatory than Neonatal Acne
-
Hyperandrogenism (e.g. adrenal cortical hyperplasia)
- Consider in severe, refractory and persistent cases
VI. Management
- Resolves spontaneously without treatment
- Treatment can be used if parents wish
- Over the counter acne soaps (low pH)
- Sparing use of Benzoyl Peroxide lotion 2.5% (test first on antecubital fossa)
VII. References
- Claudius and Behar in Herbert (2020) EM:Rap 20(8): 5-7
- Katsambas (1999) Int J Dermatol 38:128-30 [PubMed]
- O'Connor (2008) Am Fam Physician 77:47-52 [PubMed]
- Snyder (2024) Am Fam Physician 109(3): 212-6 [PubMed]
Images: Related links to external sites (from Bing)
Related Studies
Concepts | Disease or Syndrome (T047) |
ICD10 | L70.4 |
SnomedCT | 201219009, 49706007 |
Italian | Acne infantile, Acne neonatale |
Dutch | pasgeborene acne, Acne infantum, kinderacne |
French | Acné neonatorum, Acné infantile, Acné juvénile |
German | Kleinkindakne, Acne neonatorum, Acne infantum, Akne infantil |
Portuguese | Acne do recém-nascido, Acne infantil |
Spanish | Acné del recién nacido, acné infantil, acné neonatal (trastorno), acné neonatal, Acné infantil |
Japanese | 新生児ざ瘡, 乳児性ざ瘡, ニュウジセイザソウ, シンセイジザソウ |
English | infantile acne (diagnosis), neonatal acne, neonatal acne (diagnosis), infantile acne, Acne infantile, acne infantile, acne neonatorum, acne neonatal, Infantile acne (disorder), Infantile acne, Neonatal acne, Acne neonatorum, Neonatal acne (disorder) |
Czech | Akné novorozenců, Akné dětí, Dětské akné |
Korean | 유아성 여드름 |
Hungarian | Acne infantum, Acne neonatorum, Gyermekkori acne |