II. Pathophysiology

  1. Compound Nevus or Dermal Nevus
  2. Halo region is depigmented, without Melanocytes
  3. T-Lymphocyte mediated depigmentation

III. Epidemiology

  1. Onset in teen years
  2. Incidence: 1%

IV. Signs

  1. White, symmetric round halo surrounding a nevus
  2. Distribution
    1. Trunk is most typical
    2. Always spares the palms and soles

V. Associated Conditions

  1. Vitiligo risk may be increased

VI. Course

  1. Repigmentation may occur spontaneously over years

VII. Prognosis

  1. Rare malignant transformation (typically predictable by atypical features)

VIII. Reference

  1. Habif (2003) Clinical Dermatology, 4th ed.. Mosby, p. 773-813

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