II. Epidemiology

  1. Onset Age 5 months to 5 years

III. Pathophysiology

  1. Unilateral distribution following Blaschko Lines
    1. Developmental pathways of epidermal cell migration and proliferation in the fetus
  2. Unclear cause
    1. T-Cell Mediated dermatosis
    2. Epigenetic mosaicism may contribute (different cell populations with different Genotypes)
  3. Possible Triggers
    1. Viral Infection
    2. Autoimmune Conditions
    3. Pregnancy
    4. Environmental factors

IV. Findings

  1. Unilateral Linear Dermatitis along Blaschko Lines (see pathophysiology above)
    1. Typically affects extremities (rarely on Fingernails)
    2. May affect trunk
  2. Asymptomatic flesh-colored, flat topped Papules
    1. Lesions may be pruritic
    2. Erythematous Papules may be more difficult to visualize in darker skin
  3. Course
    1. Skin lesions may persist for 1-2 years
    2. Possible longer-standing skin pigmentation changes

V. Differential Diagnosis

VI. Labs

  1. Clinical diagnosis (does not require biopsy)
  2. Biopsy findings (if performed)
    1. Lymphocytic inflammatory infiltrate of Macrophages and Lymphocytes
    2. Surrounds Eccrine Glands, Hair Follicles, vessels

VII. Management

  1. No treatment needed
  2. Mild Pruritus may be treated symptomatically
    1. Topical skin Emollients
    2. Low potency Topical Corticosteroids (7-10 days)
  3. Reassurance that lesions are benign and resolve spontaneously after 1-2 years without treatment
    1. Chronic skin pigmentation changes may persist

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Related Studies

Ontology: Lichen striatus (C0263374)

Concepts Disease or Syndrome (T047)
ICD10 L44.2
SnomedCT 42442001
Dutch lichen striatus, lichen; striatus, striatus; lichen, Lichen striatus
French Lichen striatus
German Lichen striatus
Italian Lichen striatus
Portuguese Lichen striatus
Spanish Liquen estriado, liquen estriado (trastorno), liquen estriado
Japanese センジョウタイセン, 線状苔癬
English lichen striatus (diagnosis), lichen striatus, lichens striatus, lichen striata, Lichen striatus, Lichen striata, Lichen striatus (disorder), lichen; striatus, striatus; lichen, Lichen, striata
Czech Lichen striatus
Korean 선상태선
Hungarian Lichen striatus