Definition (NCI)
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A member of the pyrrolo-pyrrole group of non-steroidal anti-inflammatory drugs (NSAID) with analgesic, anti-inflammatory, and anti-pyretic properties. Tromethamine inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins. When inhibiting COX2, tromethamine may be effective in relieving pain and inflammation; when inhibiting COX1, this agent may produce unacceptable gastrointestinal side effects.
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Definition (MSH)
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An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
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Concepts |
Organic Chemical
(T109)
, Pharmacologic Substance
(T121)
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MSH |
D014325
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SnomedCT |
404882002, 59034000 |
LNC |
LP19244-0, MTHU007766 |
English |
Tris Buffer, Trisamine, Trometamol, Tromethamine, 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, Tri(hydroxymethyl)aminomethane, Tris(hydroxymethyl)aminomethane, TRIS, Aminotrimethylolmethane, Tris(hydroxymethyly)amino Methane, Tris-base, 1,3-Propanediol, 2-Amino-2-(hydroxymethyl)-, tromethamine, Abbott Brand of Trometamol, Trometamol Abbott Brand, Tham, hematological agents alkalinizers tromethamine, tromethamine (medication), TROMETHAMINE, Tromethamine [Chemical/Ingredient], tris buffer, Tromethamine (TRIS), trometamol, Tris buffer, Tromethamine (substance), Tromethamine (product) |
Swedish |
Trometamin
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Czech |
tromethamin
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Finnish |
Tris-(hydroksimetyyli)-aminometaani
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French |
Trométamol, Tham, Tri hydroxy-méthyl-aminométhane, Tampon Tris, Trométhamine, Tris(hydroxyméthyl)aminométhane |
Russian |
TROMETAMOL, TRISAMIN, TRIS-BUFER, TROMETAMIN, ТРИСАМИН, ТРИС-БУФЕР, ТРОМЕТАМИН, ТРОМЕТАМОЛ |
Japanese |
トリスアミン, トリメチロールアミノメタン, トリズマ, トリス緩衝液, トロメタミン, トロメタモール |
Polish |
THAM, Talatrol, Trometamol |
Portuguese |
Tampão Tris, Buffer Tris, Trisamina, Trometamina, Trometamol |
Spanish |
tri-buffer, tris (hidroximetil)aminometano, tri (hidroximetil)aminometano, tri-amortiguador, trometamina (sustancia), trometamina, tris-amortiguador, trometamina (producto), trometamol (sustancia), trometamol, Trisamina, Tris Buffer, Trometamina, Trometamol |
German |
Tris-Puffer, Trisamin, Trometamol, Tromethamin |
Italian |
Trometamina
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