II. Indication
- Assess whether a patient will live long enough to benefit from a specific screening measure or medical intervention
III. Scoring: Comorbidity Component (Apply 1 point to each unless otherwise noted)
- Myocardial Infarction
- Congestive Heart Failure
- Peripheral Vascular Disease
- Cerebrovascular Disease
- Dementia
- COPD
- Connective Tissue Disease
- Peptic Ulcer Disease
- Diabetes Mellitus (1 point uncomplicated, 2 points if end-organ damage)
- Moderate to Severe Chronic Kidney Disease (2 points)
- Hemiplegia (2 points)
- Leukemia (2 points)
- Malignant Lymphoma (2 points)
- Solid Tumor (2 points, 6 points if metastatic)
- Liver Disease (1 point mild, 3 points if moderate to severe)
- AIDS (6 points)
IV. Scoring: Age
- Correction
- Corrected 7/2014 (based on 1996 paper)
- Age-based scoring starts at age 50 years (not age 40 years)
- Scoring
- Age <50 years: 0 points
- Age 50-59 years: 1 points
- Age 60-69 years: 2 points
- Age 70-79 years: 3 points
V. Interpretation
- Calculate Charlson Score or Index (i)
- Add Comorbidity score to age score
- Total denoted as 'i' below
- Calculate Charlson Probablity (10 year mortality)
- Calculate Y = e^(i * 0.9)
- Calculate Z = 0.983^Y
- where Z is the 10 year survival