Topical Fluoride

Aka: Topical Fluoride, Stannous Fluoride, Dental Fluoride Treatment, Acidulated Phosphate Fluoride, Sodium Fluoride Mouthwash, Sodium Fluoride Toothpaste, ACT Rinse, Prevident, Dentagel, Crest Pro-Health Toothpaste, Gel-Kam, Phos-Flur

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II. Indications

  1. Dental carie prevention in older children and adults

III. Mechanism

  1. Fluoride inhibits tooth demineralization and promotes remineralization
  2. Fluoride inhibits plaque Bacteria

IV. Precautions

  1. Do not use Topical Fluoride in children under age 6 years
    1. See Fluoride Supplementation instead
  2. Rinse, brush or apply for 1 minute and then spit out
  3. Do not eat or drink for 30 minutes after using

V. Medications

  1. See Fluoride Supplementation
  2. Neutral Sodium Fluoride (e.g. Prevident, ACT, Dentagel, SF 5000 plus)
    1. Most common formulation used
      1. Does not etch of stain restorations or white fillings
    2. Prevident Rinse weekly (prescription)
    3. ACT Rinse daily (OTC)
    4. Dentagel
      1. Applied as thin ribbon with ToothBrush or mouth tray daily at bedtime after brushing
    5. SF 5000 Plus
      1. Use in place of regular toothpaste at bedtime
  3. Acidulated Phosphate Fluoride (e.g. Phos-Flur)
    1. Prevents white demineralization areas (e.g. braces)
  4. Stannous Fluoride (e.g. Crest Pro-Health Toothpaste, Gel-Kam)
    1. Offers protection against tooth sensitivity and Gingivitis
    2. Risk of tooth staining

VI. Resources

  1. CDC Fluoride
    1. http://www.cdc.gov/fluoridation/fluoride_products/

VII. References

  1. (2013) Presc Lett 20(9): 53-4
  2. (2025) Presc Lett 32(5): 27-8
  3. Nassar Y, Brizuela M (2023) The Role of Fluoride on Caries Prevention, StatPearls +PMID: 36508516 [PubMed]

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Cost: Medications

dentagel (on 7/5/2023 at Medicaid.Gov Survey of pharmacy drug pricing)
DENTAGEL 1.1% GEL Generic $0.14 per gram
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Minerals and Other Inorganic Chemicals

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