Infectious Causes of Neutropenia

Aka: Infectious Causes of Neutropenia, Neutropenia due to Infection

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II. Pathophysiology

  1. Infection is most common cause of acquired Neutropenia
  2. Infectious Neutropenia is often via marrow injury
  3. Granulomatous infections infiltrate marrow

III. Causes: Severe Neutropenia

  1. Bacterial Sepsis (especially Gram Negative Bacteria)
  2. Infectious Mononucleosis
  3. Hepatitis B Virus
  4. Human Immunodeficiency Virus (HIV)

IV. Causes: Viral Infections

  1. Infectious Mononucleosis (common)
  2. Hepatitis B Virus
  3. Human Immunodeficiency Virus (HIV Infection)
  4. Measles
  5. Mumps
  6. Rubella
  7. Roseola (HH6, common)
  8. Malaria
  9. Leishmaniasis
  10. Cytomegalovirus
  11. Colorado Tick Fever
  12. Influenza
  13. Dengue Fever
  14. Viral Hepatitis
  15. Herpes Simplex Virus
  16. Parvovirus B19 (common)
  17. Respiratory Syncytial Virus
  18. Small Pox
  19. Varicella
  20. Yellow Fever

V. Causes: Bacterial Infections

  1. Tuberculosis
  2. Typhoid Fever
  3. Brucellosis
  4. Tularemia
  5. Rocky Mountain Spotted Fever

VI. Causes: Fungal Infections

  1. Histoplasmosis

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