II. Pathophysiology

  1. Infected cystic blood filled spaces in hepatic lobules
  2. Complication of Bacillary Angiomatosis caused by Bartonella Henselae (or B. quintana)
  3. Occurs in AIDS (CD4 Count <100 cells/mm3) or other immunocompromised patients

III. Symptoms

  1. Anorexia
  2. Nausea
  3. Abdominal Pain
  4. Fever
  5. Weight loss
  6. Vascular skin lesions
    1. Distinguish from Kaposi's Sarcoma
  7. Disseminated infection (complicated cases)
    1. May infect bone, mucosa, CNS or Heart Valves (endocarditis)

IV. Labs

  1. Bartonella Henselae (or B. quintana) Antibody titer increases

V. Imaging

  1. Right upper quadrant Ultrasound
    1. Hepatic Cystic lesions (or splenic lesions)
    2. Distinguish from Liver Abscess

VI. Management

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Ontology: Peliosis Hepatis (C0030781)

Definition (MSH) A vascular disease of the LIVER characterized by the occurrence of multiple blood-filled CYSTS or cavities. The cysts are lined with ENDOTHELIAL CELLS; the cavities lined with hepatic parenchymal cells (HEPATOCYTES). Peliosis hepatis has been associated with use of anabolic steroids (ANABOLIC AGENTS) and certain drugs.
Concepts Disease or Syndrome (T047)
MSH D010382
ICD10 K76.4
SnomedCT 197366003, 58008004, 240625009
English Hepatis, Peliosis, Peliosis Hepatis, PELIOSIS HEPATIS, peliosis hepatis, peliosis hepatis (diagnosis), Peliosis hepatitis, Peliosis Hepatis [Disease/Finding], hepatic peliosis, peliosis hepatitis, Peliosis hepatis, Telangiectasis of liver, Hepatic peliosis, PH - Peliosis hepatis, Hepatic peliosis (disorder), Peliosis hepatis (disorder), Hepatis peliosis, hepatis; peliosis, liver; angiomatosis, peliosis; hepatis, angiomatosis; liver
Dutch purpura hepatitis, angiomatose; lever, hepatis; peliosis, lever; angiomatose, peliosis; hepatis, hepatische purpura, Peliosis hepatis
German Peliosis hepatitis, Hepatis peliosis, Peliosis hepatis
Italian Epatite peliosica, Peliosi epatica
Spanish Hepatitis con peliosis, peliosis hepática (trastorno), peliosis hepática, telangiectasias del hígado (trastorno), telangiectasias del hígado, Peliosis hepática, Peliosis Hepática
Japanese 肝臓紫斑病, カンゾウシハンビョウ
Swedish Peliosis hepatis
Czech peliosis hepatis, Peliosis hepatis
Finnish Maksan pelioosi
Russian PELIOZ PECHENI, PECHENI PELIOZ, ПЕЛИОЗ ПЕЧЕНИ, ПЕЧЕНИ ПЕЛИОЗ
Korean 간자색반병
Polish Plamica wątrobowa
Hungarian Peliosis hepatis, máj peliosis, Peliosisos hepatitis
Norwegian Hepatisk peliose, Peliosis hepatis
Portuguese Peliose hepática, Peliose Hepática
French Péliose hépatique, Péliose du foie

Ontology: Bacillary peliosis (C0343770)

Concepts Disease or Syndrome (T047)
SnomedCT 240624008
English Bacillary peliosis, Bacillary peliosis (disorder)
Spanish peliosis bacilar (trastorno), peliosis bacilar

Ontology: Bacillary peliosis hepatis (C1504483)

Concepts Disease or Syndrome (T047)
Dutch bacillaire peliosis hepatis
French Péliose hépatique baccilaire
German bazillaere Peliosis hepatis
Italian Peliosi bacillare del fegato
Portuguese Peliose hepática bacilar
Spanish Peliosis hepática bacilar
Japanese 細菌性肝臓紫斑病, サイキンセイカンゾウシハンビョウ
Czech Bacilární jaterní pelióza
Hungarian Bacillaris peliosis hepatis
English Bacillary peliosis hepatis