II. Definitions
- Prurigo Nodularis
- Firm, pruritic Nodules, esp. on the arms and legs, forming in response to scratching
III. Epidemiology
- Bimodal age distribution
- Younger patients with Atopic Dermatitis and environmental allergies
- Older patients without Atopic Dermatitis or environmental allergies
IV. Risk Factors
- Actopic Dermatitis
- Young women
V. Pathophysiology
- Intense Pruritus leads to excessive scratching
VI. Signs
VII. Management
- Intralesional Triamcinolone injection
- High potency Corticosteroid under Occlusion
-
Thalidomide has been used for severe cases
- Serious Teratogenicity (in addition to other precautions)
-
Neurontin 300 mg orally three times daily
- May reduce intense itching and scratching cycles
VIII. References
- Wolff (2017) Fitzpatrick's Color Atlas of Clinical Dermatology, McGraw Hill, Chicago, p. 42
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Related Studies
| Concepts | Disease or Syndrome (T047) |
| ICD10 | L28.1 |
| SnomedCT | 63501000 |
| Dutch | prurigo nodularis, nodularis; prurigo, prurigo; nodularis, Prurigo nodularis |
| French | Prurigo nodulaire de Hyde |
| German | Prurigo nodularis |
| Italian | Prurigo nodularis |
| Portuguese | Prurigo nodular |
| Spanish | Prurigo nodular, enfermedad de Hyde, prurigo nodular (trastorno), prurigo nodular |
| Japanese | 結節性痒疹, ｹｯｾﾂｾｲﾖｳｼﾝ |
| English | prurigo nodularis, prurigo nodularis (diagnosis), hyde's disease, Hyde's disease, Prurigo nodularis (disorder), nodular; prurigo, prurigo; nodular, Prurigo nodularis |
| Czech | Prurigo nodularis |
| Korean | 결절성 가려움발진 |
| Hungarian | Prurigo nodularis |
