II. Epidemiology
- Accounts for one third of Nephrotic Syndrome in adults
- Peak Incidence 30 to 50 years old
III. Causes
- Idiopathic (75%)
- Systemic Lupus Erythematosus
- Hepatis B Virus Infection
- Drug-induced Nephrotic Syndrome
- Cancer
IV. Labs
-
Urinalysis
- Microscopic Hematuria (variably present)
V. Labs: Pathology
- Thickening of glomerular basement membrane on electron microscopy
- IgG and C3 depositis with immunofluorescent stains