II. Physiology

  1. Transport Proteins aid in substance transfer in and out of the cell

III. Pathophysiology

  1. Transport Proteins may interfere with drug absorption, distribution and elimination

IV. Types

  1. Breast Cancer Resistance Protein (BCRP)
  2. Organic Anion Transport Protein (e.g. OATP1B1, OATP1B3)
  3. Organic Cation Transport Protein (e.g. OCT2)
  4. Multidrug and Toxin Exctrusion Protein (e.g. MATE1, MAE2-K)

V. References

  1. (2022) presc lett 29(8): 47-8

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