Powassan Encephalitis

Aka: Powassan Encephalitis, Powassan Tick-Borne Encephalitis, Powassan Viral Encephalitis, Powassan Virus

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II. Epidemiology

  1. Rare Encephalitis cause in Northeastern and North Central States

III. Pathophysiology

  1. Tickborne Illness via Woodchuck Tick or Groundhog Tick (Ixodes cookei, I. marxi or I. Scapularis)

IV. Findings

  1. Presentations range from asymptomatic to severe neurologic Impairment

V. Labs

  1. Antibody to Powassan Virus (serum, CSF)

VI. Differential Diagnosis

  1. See Encephalitis

VII. Management

  1. No known effective treatment
  2. Supportive care

VIII. Prognosis

  1. Cognitive Impairment in >50% of survivors, and 10-15% mortality

IX. Resources

  1. Powassan Virus (CDC)
    1. https://www.cdc.gov/powassan/clinicallabeval.html

X. References

  1. Birge (2012) Emerg Infect Dis 18(10):1669-71 +PMID: 23017222 [PubMed]
  2. Hermance (2017) Vector Borne Zoonotic Dis 17(7):453-62 +PMID: 28498740 [PubMed]

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Related Studies

Ontology: Powassan Encephalitis (C0032858)

Concepts Disease or Syndrome (T047)
MSH D004675
SnomedCT 80110006, 416543004
English Encephalitis, Powassan, POWASSAN ENCEPH, Powassan encephalitis (diagnosis), Powassan tick-borne encephalitis, Powassan viral encephalitis, Powassan Encephalitides, Encephalitides, Powassan, Powassan encephalitis (disorder), Powassan; encephalitis, encephalitis; Powassan, Powassan Encephalitis, Powassan encephalitis, Neuroinvasive Powassan encephalitis virus infection (disorder), Neuroinvasive Powassan encephalitis virus infection
Portuguese Encefalite por Vírus Powassan
Spanish Encefalitis de Powassan, encefalitis por virus Powassan, encefalitis por virus Powassan (trastorno), infección neuroinvasiva por virus de la encefalitis de Powassan (trastorno), infección neuroinvasiva por virus de la encefalitis de Powassan
French Encéphalite de Powassan
German Powassan-Enzephalitis
Italian Encefalite di Powassan
Norwegian Powassan-encefalitt
Czech encefalitida Powassan
Dutch Powassan; encefalitis, encefalitis; Powassan, Powassan-encefalitis
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Powassan virus (C0032859)

Concepts Virus (T005)
MSH D004669
SnomedCT 45838003
LNC LP21134-9
Czech virus Powassan
Portuguese Vírus Powassan
Spanish Virus Powassan, virus Powassan (organismo), virus Powassan
German Powassan-Virus
French Virus de Powassan, Virus Powassan, Powassan virus
English Flavivirus powassan, Powassan virus (organism), Powassan virus
Dutch Powassan-virus
Derived from the NIH UMLS (Unified Medical Language System)

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