II. Epidemiology
- No increase in fetal malformations noted
III. Management
- Pregnancy
- Most Antibiotics may be used
- Avoid Tetracyclines
- Quinolones are not Teratogenic
- Beta Adrenergic Agonists may be used
- Most Antibiotics may be used
- Delivery
- Avoid general Anesthesia and Narcotics
- Epidural Anesthesia is preferred for analgesia
- Avoid prolonged labor (maternal exhaustion)
-
Lactation
- Healthy mothers with Cystic Fibrosis may Breast feed
- Breast Milk does not contain excess Sodium
- Essential Fatty Acids and fat content is lower
IV. Complications
- Low Weight Gain in Pregnancy
- Cystic Fibrosis exacerbation
- Preterm delivery rate: 6 to 35%
V. Prognosis
- Factors associated with best pregnancy outcomes
- FEV1 >80%
- No Burkholderia cepacia colonization
- Factors predicting pregnancy complications