II. Epidemiology
- Northwest United States
- Peak onset in spring: April to June
III. Pathophysiology
- Neurotoxin secretion during tick attachment or feeding via Saliva (non-infectious)
- Occurs with Female ticks of several species
- Dermacentor (e.g. American Dog Tick, Rocky Mountain Wood Tick)
- Amblyomma (e.g. Gulf Coast Tick)
- Ixodes
IV. Findings
- Acute ascending Flaccid Paralysis
- Onset 2-6 days after Tick Bite
- Neurologic progression
- Difficulty walking or standing
- Ataxia
- Absent Deep Tendon Reflexes
- Drooling
- Tachypnea
- Girls under age 10 years old may have unique presentations
- Ataxia
- Weakness without sensory loss
- Graham (2011) Pediatr Emerg Care 27(2): 141-7 [PubMed]
V. Differential Diagnosis
-
Guillain-Barre Syndrome
- Tick Paralysis progresses more rapidly than Guillain-Barre Syndrome
VI. Management
- Removal of tick is curative (typically within 24 hours)
VII. Prevention
VIII. Prognosis: Unrecognized infection (tick not removed)
- Progresses to Respiratory Failure and death
IX. References
- Green and Millsap (2016) Crit Dec Emerg Med 30(1): 4
- Pensa and Werner in Swadron (2022) EM:Rap 22(5): 8-12