II. Differential Diagnosis
III. Pathophysiology
- Occurs after Lone Star Tick (Amblyomma Americanum) bite in southeastern and eastern states
- Unknown cause
- Borrelia lonestari association has been disproven
IV. Findings
- Viral-type prodromal symptoms (feve, Headache, Fatigue, myalgias)
- Circular or bullseye rash
- Similar to Erythema Migrans of Lyme Disease, but not caused by Borrelia Burgdorferi
- Rash onset from time of Tick Bite is typically by Day 6-7 on average (sooner than with Lyme Disease)
- STARI Lesions are typically smaller (6-10 cm) than for Lyme Disease (6-28 cm)
- STARI lesions are most often single (may be multiple in Lyme Disease)
V. Associated Conditions: Other Illnesses carried by Lone Star Tick
- Tularemia
- Ehrlichiosis
- Heartland Virus
- Bourbon Virus
- Alpha-Gal Syndrome
VI. Management
-
Doxycycline
- STARI improves with Doxycycline (but known if antibiotics modify course)
- However, STARI and Lyme Disease may be difficult to distinguish, and Doxycycline is critical for lymes
VII. Prognosis
- No association with longterm, chronic complications (e.g. Arthritis, neurologic deficits)
VIII. Resources
- STARI (CDC)
Images: Related links to external sites (from Bing)
Related Studies
| Concepts | Disease or Syndrome (T047) |
| SnomedCT | 444100007 |
| English | Southern tick-associated rash illness (disorder), STARI - Southern tick-associated rash illness, Southern tick-associated rash illness, Masters disease |
| Spanish | enfermedad exantemática del sudeste asociada a garrapatas, enfermedad exantemática del sudeste asociada a garrapatas (trastorno), enfermedad de Masters |
