II. Red Flags: Birth to three month
- Rolling prior to 3 months- Evaluate for hypertonia
 
- Persistent fisting at 3 months- Evaluate for neuromotor dysfunction
 
- Failure to alert to environmental stimuli- Evaluate for sensory Impairment
 
III. Red Flags: 4 to 6 months
- Poor head control- Evaluate for hypotonia
 
- Failure to reach for objects by 5 months- Evaluate for motor, visual or cognitive deficits
 
- Absent Smile- Evaluate for visual loss
- Evaluate for attachment problems
- Evaluate maternal Major Depression
- Consider Child Abuse or child neglect in severe cases
 
IV. Red Flags: 6 to 12 months
- Persistence of primitive reflexes after 6 months- Evaluate for neuromuscular disorder
 
- Absent babbling by 6 months- Evaluate for Hearing Deficit
 
- Absent stranger anxiety by 7 months- May be related to multiple care providers
 
- W-sitting and bunny hopping at 7 months- Evaluate for adductor spasticity or hypotonia
 
- Inability to localize sound by 10 months- Evaluate for unilateral Hearing Loss
 
- Persistent mouthing of objects at 12 months- May indicate lack of intellectual curiosity
 
V. Red Flags: 12 to 24 months
- Lack of consonant production by 15 months- Evaluate for Mild Hearing Loss
 
- Lack of imitation by 16 months- Evaluate for Hearing Deficit
- Evaluate for cognitive or socialization deficit
 
- Lack of protodeclarative pointing by 18 months- Problem in social relatedness
 
- Hand dominance prior to 18 months- May indicate contralateral weakness with Hemiparesis
 
- Inability to walk up and down stairs at 24 months- May lack opportunity rather than motor deficit
 
- Persistent poor transitions in 21 to 24 months- May indicate pervasive Developmental Disorder
 
- Advanced non-communicative speech (e.g. Echolalia)- Simple commands not understood suggests abnormality
- Evaluate for Autism
- Evaluate for pervasive Developmental Disorder
 
- Delayed Language Development- Requires Hearing Loss Evaluation in all children
 
VI. Management: Immediate speech therapy evaluation indications
VII. Resources
- Georgetown Bright Futures Provider Guidelines
VIII. References
- Frankenburg (1990) Denver II Developmental Screening
- Blondis (1999) Pediatr Clin North Am 46:899-913 [PubMed]
