II. Epidemiology

  1. Onset typically over age 55 years (although younger ages may be affected)

III. Pathophysiology

  1. Malignant variant of leiomyoma (e.g. Uterine Fibroid)
  2. Aggressive, Smooth Muscle connective tissue tumor
  3. Neoplastic spindle cell proliferation

IV. Findings

  1. Expanding mass on the limbs, head, neck, Abdomen or retroperioneum
  2. Symptoms are related to location of mass (e.g. Abdominal Pain)

V. Imaging

  1. CT with Contrast
    1. Heterogeneous mass

VI. Management

  1. Refer for core needle biopsy and surgical resection

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