II. Causes

  1. Isoimmunization or Hemolytic Disease of the Newborn
    1. Rh Sensitization
    2. ABO Incompatibility
    3. Other autoantibodies
    4. Glucose 6 phosphate deficiency (G6PD)
  2. Fetal Hemorrhage
    1. Perinatal Trauma
    2. Tumors
    3. Twin to twin transfusion
  3. Red cell production defect
    1. Congenital Parvovirus B19 infection
    2. Diamond-Blackfan Syndrome
    3. Alpha-Thalassemia
    4. Hereditary Spherocytosis

III. Signs (Fetal hydrops)

  1. Large Placenta at delivery
  2. Yellow vernix caseosa
  3. Jaundice
  4. Purpura
  5. Cyanosis
  6. Abdominal Distention
    1. Hepatomegaly
    2. Splenomegaly
    3. Ascites
  7. Scalp Edema results in Halo appearance
  8. Ribs splayed
  9. Abduction of limbs (Budha attitude)
  10. Loss of flexion

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Ontology: Hydrops Fetalis (C0020305)

Definition (NCI) A condition characterized by fluid accumulation in two or more anatomic compartments in the fetus.(NICHD)
Definition (MSH) Abnormal accumulation of serous fluid in two or more fetal compartments, such as SKIN; PLEURA; PERICARDIUM; PLACENTA; PERITONEUM; AMNIOTIC FLUID. General fetal EDEMA may be of non-immunologic origin, or of immunologic origin as in the case of ERYTHROBLASTOSIS FETALIS.
Concepts Disease or Syndrome (T047)
MSH D015160
ICD10 P83.2
SnomedCT 268879006, 157134005, 276508000, 59928009
English Fetal Hydrops, Hydrops, Fetal, HYDROPS FETALIS, Edema, Fetal, Fetal Edema, Fetal hydrops, Hydrops foetalis, Hydrops fetalis NOS, Hydrops Fetalis [Disease/Finding], hydrops fetalis, hydrops foetalis, fetal edema, fetalis hydrops, fetal hydrops, hydrops fetal, Hydrops Fetalis, Hydrops fetalis, HF - Hydrops fetalis, Hydrops fetalis (disorder), hydrops; fetal, Hydrops fetalis, NOS, Hydrops foetalis, NOS
French ANASARQUE FOETO-PLACENTAIRE, Hydropisie foetale, Anasarque foetoplacentaire, Anasarque foeto-placentaire, Anasarque foetal
Spanish HYDROPS FETALIS, Hidropsia Fetal, Hidropesía Fetal, hidropesía fetal (trastorno), hidrops fetal, hidropesía fetal, hidrops fetal (trastorno), Hidropesía fetal, Edema Fetal
Swedish Hydrops fetalis
Japanese タイジスイシュ, 先天性胎児水腫, 胎児水腫, 胎児水症
Czech hydrops fetalis, Hydrops fetalis, Hydrops plodu
Finnish Sikiön vesipöhö
Portuguese HYDROPS FETALIS, Hidropsia Fetal, Hidropisia Fetal, Anasarca fetal, Edema Fetal
German HYDROPS FOETALIS, Fetaler Hydrops, Hydrops fetalis, Hydrops neonatorum, Hydrops, angeborener, Fetales Ödem, Ödem, fetales
Italian Edema fetale, Idrope fetale
Polish Puchlina płodowa, Wodniak płodowy
Hungarian Hydrops foetalis, Foetalis hydrops
Norwegian Føtal hydrops, Føtalt ødem, Hydrops foetalis
Dutch hydrops; foetaal, hydrops foetalis, Foetaal oedeem, Foetale hydrops, Hydrops, foetalis, Oedeem, foetaal