II. Epidemiology
- Seen primarily in advanced HIV in Caribbean, SW USA
III. Pathophysiology
- Gastrointestinal infection
IV. Differential Diagnosis
V. Diagnosis
- Stool Acid Fast Stain
VI. Management
- Trimethoprim-sulfamethoxazole (Bactrim, Septra, TMP-SMZ) DS
- Alternative agents
- Pyrimethamine 50 to 75 mg orally daily and folinic acid 10-25 mg orally daily
- Ciprofloxacin 500 mg twice daily for 7 days (limited evidence)
VII. Course
- Relapse in 50% of patients
- Chronic suppressive therapy may be necessary
- Example: Septra DS 1 tab orally three times weekly or once orally daily
VIII. References
- Gilbert (2016) Sanford Guide, on IOS, accessed 9/12/2016
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Related Studies
| Concepts | Eukaryote (T204) |
| SnomedCT | 12633005 |
| Dutch | Isospora belli |
| French | Isospora belli |
| German | Isospora belli |
| Italian | Isospora belli |
| Portuguese | Isospora belli |
| Japanese | イソスポーラ・ベリ, ｲｿｽﾎﾟｰﾗﾍﾞﾘ |
| English | Isospora belli, Cystoisospora belli, isospora belli, Isospora belli (organism) |
| Czech | Isospora belli |
| Hungarian | Isospora belli |
| Spanish | Isospora belli (organismo), Isospora belli |
Ontology: Isosporiasis (C0311386)
| Definition (MSH) | Infection with parasitic protozoa of the genus ISOSPORA, producing intestinal disease. It is caused by ingestion of oocysts and can produce tissue cysts. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D021865 |
| ICD10 | A07.3 |
| SnomedCT | 73034009, 360427001, 240373006, 371423007 |
| LNC | LA10479-6 |
| Japanese | イソスポーラ症, ｲｿｽﾎﾟｰﾗｼｮｳ |
| Swedish | Isosporiasis |
| Czech | isosporiasis, izosporóza, Izosporóza |
| Finnish | Isosporiaasi |
| Russian | IZOSPORIAZ, ИЗОСПОРИАЗ |
| English | isosporiasis (diagnosis), isosporiasis, Isosporiasis [Disease/Finding], isosporosis, Isosporiases, Isosporosis, Isosporiasis (disorder), Isosporiasis, Isosporiasis (disorder) [Ambiguous], Infection by Isospora belli and Isospora hominis |
| Korean | 등포자충증 |
| Polish | Izosporoza, Zarażenie Isospora |
| Hungarian | isosporiasis |
| Spanish | isosporosis, isosporiasis (concepto no activo), isosporiasis (trastorno), isosporiasis, Isosporiasis |
| Dutch | isosporiasis, Isosporiasis |
| French | Isosporose, Isosporidiose |
| German | Isosporiasis, Isosporose, Isospora-Infektion |
| Italian | Isosporiasi |
| Portuguese | Isosporíase |
