II. Grading: Gleason Grade
- Score
- Grade dominant Prostate tumor on scale 1 to 5
- Grade other histologic patterns on scale 1 to 5
- Sum 2 grades for total score of 2 to 10 for tumor
- Interpretation: Prostate Cancer histology
- Grade 2 suggests highly differentiated tumor (best)
- Grade 10 suggests undifferentiated tumor (worst)
III. Grading: Grade Group (GG)
- Score
- Grade Group 1: Equivalent to Gleason Score of 6 (3+3)
- Grade Group 2: Equivalent to Gleason Score of 7 (3+4)
- Grade Group 3: Equivalent to Gleason Score of 7 (4+3)
- Grade Group 4: Equivalent to Gleason Score of 8 (4+4)
- Grade Group 5: Equivalent to Gleason Score of 9 or 10 (4+5 or 5+5)
- Interpretation
- GG1 lesions are associated with very low mortality
- Most Prostate Cancer Management is focused on GG2 and higher
IV. Reference
- Wilson (1991) Harrison's Internal Medicine, p. 1630
- Pierorazio (2013) BJU Int 111(5): 753-60 +PMID: 23464824 [PubMed]
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Related Studies
| Definition (MSH) | System of grading PROSTATE CANCER based on the degree of abnormality of the glandular archtecture of the tumor. |
| Definition (NCI) | A grading system for prostatic carcinoma based on the microscopic glandular architectural patterns of the malignant epithelial cells. Nuclear atypia is not evaluated. It defines five patterns or grades which reflect decreasing differentiation. |
| Concepts | Classification (T185) |
| MSH | D060787 |
| SnomedCT | 393947006, 394930000, 392991003, 106241006 |
| Spanish | sistema de puntaje de Gleason para cáncer prostático, clasificación de Gleason del cáncer prostático, clasificación de Gleason del cáncer prostático (escala de estadificación), sistema de clasificación de Gleason mediante microscopia del carcinoma prostático (escala de estadificación), sistema de clasificación de Gleason mediante microscopia del carcinoma prostático, sistema de puntaje de Gleason mediante microscopia del carcinoma prostático (escala de estadificación), sistema de puntaje de Gleason mediante microscopia del carcinoma prostático, sistema de puntaje de Gleason para cáncer prostático (escala de estadificación), sistema de puntaje de Gleason para del cáncer prostático |
| English | Gleason's prostatic grading, Gleason Grade for Prostate Cancer, gleason grading, gleason grading scoring, gleason scores, gleason score, gleasons grade, gleason grade, gleasons grading scoring, Gleason Grading, Grading, Gleason, Gleason Grading System, Gleason grading of prostate cancer (staging scale), Gleason grading of prostate cancer (tumor staging), Gleason grading of prostate cancer, Gleason's microscopic prostatic carcinoma grading system, Gleason grading for prostatic cancer, Gleason grading system for prostatic cancer (staging scale), Gleason grading system for prostatic cancer, Gleason grading for prostatic cancer (staging scale), Gleason's microscopic prostatic carcinoma grading system (staging scale), Gleason Grade |
| French | Évaluation du grade de Gleason, Grading de Gleason, Détermination du grade de Gleason, Établissement du grade de Gleason |
| Czech | Gleasonův systém |
| German | Gleason-Klassifikation |
| Norwegian | Gleason-gradering |
